Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | GAA | P10253 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18862985 | 1.00 | KMT2A (0.58) | KMT2AMAPTALDH1A1GAAHTT | |
| SCHEMBL28587201 | 0.84 | ALDH1A1 (0.56) | KMT2AMAPTALDH1A1GAAHTT | |
| SCHEMBL4703427 | 0.81 | CYP1A2 (0.56) | KMT2AMAPTALDH1A1GAAHTT | |
| SCHEMBL4703428 | 0.81 | CYP1A2 (0.56) | KMT2AMAPTALDH1A1GAAHTT | |
| SCHEMBL27743048 | 0.81 | CYP1A2 (0.56) | KMT2AMAPTALDH1A1GAAHTT | |
| SCHEMBL18862977 | 0.77 | MAPK1 (0.60) | KMT2AMAPTALDH1A1GAAHTT | |
| SCHEMBL18862976 | 0.77 | MAPK1 (0.60) | KMT2AMAPTALDH1A1GAAHTT | |
| SCHEMBL8858950 | 0.76 | MAPK1 (0.59) | KMT2AMAPTALDH1A1ESR1CYP19A1 | |
| SCHEMBL671514 | 0.74 | GSK3B (0.67) | ALDH1A1GAAESR1CYP19A1ESR2 | |
| SCHEMBL15057638 | 0.74 | TSHR (0.62) | KMT2AMAPTALDH1A1GAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9845295-B2 | Triphenylethylene compounds and uses thereof | PURDUE RESEARCH FOUNDATION (US) | 2017-12-19 | — | — | US | disclosed |
| US-20170144975-A1 | TRIPHENYLETHYLENE COMPOUNDS AND USES THEREOF | PURDUE RESEARCH FOUNDATION | 2017-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170144975-A1 | TRIPHENYLETHYLENE COMPOUNDS AND USES THEREOF | CYP19A1, ESR1, ESRRA | KMT2A 296/4885MAPT 3468/4885ALDH1A1 1103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.