SCHEMBL28587201

SCHEMBL28587201

CCC(=NO)c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.56
MAPT P10636 4/20 0.56
KMT2A Q03164 3/20 0.56
GAA P10253 1/20 0.56
HTT P42858 1/20 0.56
MAPK1 P28482 1/20 0.52
CES1 P23141 2/20 0.50
ESR1 P03372 1/20 0.50
CYP19A1 P11511 1/20 0.50
ESR2 Q92731 1/20 0.50
MEN1 O00255 2/20 0.49
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
GSK3B P49841 1/20 0.47
TSHR P16473 1/20 0.47
CYP1A2 P05177 1/20 0.45
CYP2C19 P33261 1/20 0.45
CES2 O00748 1/20 0.44
SRD5A2 P31213 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18862985 0.84 KMT2A (0.58) ALDH1A1MAPTKMT2AGAAHTT
SCHEMBL18862986 0.84 KMT2A (0.58) ALDH1A1MAPTKMT2AGAAHTT
SCHEMBL10792016 0.82 TSHR (0.52) ALDH1A1MAPTKMT2AGAAMAPK1
SCHEMBL11442366 0.80 MAPK1 (0.42) ALDH1A1MAPTKMT2AGAAHTT
SCHEMBL8021779 0.79 TDP1 (0.55) ALDH1A1MAPTKMT2AGAAHTT
SCHEMBL8021776 0.79 TDP1 (0.55) ALDH1A1MAPTKMT2AGAAHTT
SCHEMBL28552872 0.78 CES1 (0.46) ALDH1A1MAPTGAAHTTMAPK1
SCHEMBL28552870 0.78 CES1 (0.46) ALDH1A1MAPTGAAHTTMAPK1
SCHEMBL17973372 0.78 MAPK1 (0.47) ALDH1A1MAPTKMT2AGAAHTT
SCHEMBL8858950 0.77 MAPK1 (0.59) ALDH1A1MAPTKMT2AMAPK1CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113173829-A Catalysis method for preparing amide through Beckmann rearrangement reaction of ketoxime 清华大学 2021-07-27 CN claimed
CN-113173829-A Catalysis method for preparing amide through Beckmann rearrangement reaction of ketoxime 清华大学 2021-07-27 CN disclosed