Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH1 | Q92800 | 9/20 | 0.64 |
| ▸ | EZH2 | Q15910 | 13/20 | 0.62 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.56 |
| ▸ | EED | O75530 | 1/20 | 0.56 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.56 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.56 |
| ▸ | RBBP7 | Q16576 | 1/20 | 0.56 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.56 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19620816 | 0.88 | EZH2 (0.48) | EZH1EZH2PRMT3EEDRBBP4 | |
| SCHEMBL2594803 | 0.86 | EZH1 (0.82) | EZH1EZH2PRMT3EEDRBBP4 | |
| SCHEMBL20991983 | 0.84 | EZH1 (0.70) | EZH1EZH2PRMT3EEDRBBP4 | |
| SCHEMBL2592678 | 0.79 | EZH2 (0.81) | EZH1EZH2PRMT3EEDRBBP4 | |
| SCHEMBL20992055 | 0.79 | EZH2 (0.81) | EZH1EZH2PRMT3EEDRBBP4 | |
| SCHEMBL30956686 | 0.79 | EZH2 (0.81) | EZH1EZH2PRMT3EEDRBBP4 | |
| SCHEMBL24227145 | 0.79 | EZH2 (0.58) | EZH1EZH2PRMT3EEDRBBP4 | |
| SCHEMBL23863738 | 0.79 | EZH2 (0.72) | EZH1EZH2PRMT3EEDRBBP4 | |
| SCHEMBL12180173 | 0.78 | EZH2 (0.86) | EZH1EZH2PRMT3EEDRBBP4 | |
| SCHEMBL2591377 | 0.78 | EZH1 (1.00) | EZH1EZH2PRMT3EEDRBBP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9649307-B2 | Indoles | GLAXOSMITHKLINE LLC (US) | 2017-05-16 | — | — | US | disclosed |