Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.61 |
| ▸ | GNG2 | P59768 | 5/20 | 0.61 |
| ▸ | GNB1 | P62873 | 5/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | RECQL | P46063 | 2/20 | 0.54 |
| ▸ | CASP6 | P55212 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | APEX1 | P27695 | 2/20 | 0.54 |
| ▸ | NSD2 | O96028 | 1/20 | 0.54 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.54 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1592210 | 0.89 | GNG2 (0.76) | P2RY12GNG2GNB1HSD17B10CYP1A2 | |
| SCHEMBL11425330 | 0.84 | ALDH1A1 (0.58) | P2RY12GNG2GNB1HSD17B10CYP1A2 | |
| SCHEMBL18867032 | 0.81 | GNG2 (0.71) | P2RY12GNG2GNB1HSD17B10CYP1A2 | |
| SCHEMBL14642058 | 0.80 | GNG2 (0.66) | P2RY12GNG2GNB1HSD17B10CYP1A2 | |
| SCHEMBL10609900 | 0.79 | GNG2 (0.71) | P2RY12GNG2GNB1HSD17B10CYP1A2 | |
| SCHEMBL14069692 | 0.79 | GNG2 (0.67) | P2RY12GNG2GNB1HSD17B10CYP1A2 | |
| SCHEMBL11321111 | 0.78 | GNG2 (0.81) | P2RY12GNG2GNB1HSD17B10CYP1A2 | |
| SCHEMBL8643316 | 0.78 | GNG2 (0.61) | P2RY12GNG2GNB1HSD17B10CYP1A2 | |
| SCHEMBL13214102 | 0.78 | GNG2 (0.73) | P2RY12GNG2GNB1HSD17B10CYP1A2 | |
| SCHEMBL11425002 | 0.77 | GNG2 (0.68) | P2RY12GNG2GNB1HSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2129653-B1 | NOVEL P2Y12 RECEPTOR ANTAGONISTS | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2017-05-17 | — | — | EP | disclosed |