Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNG2 | P59768 | 4/20 | 0.55 |
| ▸ | GNB1 | P62873 | 4/20 | 0.55 |
| ▸ | P2RY4 | P51582 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | PLAUR | Q03405 | 3/20 | 0.52 |
| ▸ | MAP2K7 | O14733 | 2/20 | 0.50 |
| ▸ | CDC25B | P30305 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NSD2 | O96028 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13214014 | 0.85 | GNG2 (0.76) | GNG2GNB1P2RY4ALDH1A1MAPK1 | |
| SCHEMBL3033166 | 0.84 | GNG2 (0.74) | GNG2GNB1P2RY4ALDH1A1MAPK1 | |
| SCHEMBL3364421 | 0.79 | GNG2 (0.56) | GNG2GNB1P2RY4ALDH1A1MAPK1 | |
| SCHEMBL3364414 | 0.79 | GNG2 (0.56) | GNG2GNB1P2RY4ALDH1A1MAPK1 | |
| SCHEMBL3033165 | 0.77 | P2RY4 (0.80) | P2RY4MEN1KMT2AP2RY12P2RY2 | |
| SCHEMBL14066759 | 0.76 | GNG2 (0.61) | GNG2GNB1P2RY4ALDH1A1MAPK1 | |
| SCHEMBL13214019 | 0.74 | P2RY4 (0.80) | GNG2GNB1P2RY4ALDH1A1MAPK1 | |
| SCHEMBL19359475 | 0.74 | PLAUR (0.69) | GNG2GNB1P2RY4ALDH1A1MAPK1 | |
| SCHEMBL10794537 | 0.74 | CDC25B (0.61) | ALDH1A1MAPK1CYP1A2PLAURMAP2K7 | |
| SCHEMBL13214011 | 0.74 | P2RY12 (0.81) | GNG2GNB1P2RY4ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2129653-B1 | NOVEL P2Y12 RECEPTOR ANTAGONISTS | Rheinische Friedrich-Wilhelms-Universität Bonn (DE) | 2017-05-17 | — | — | EP | disclosed |