Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAUR | Q03405 | 3/20 | 0.69 |
| ▸ | P2RY4 | P51582 | 5/20 | 0.54 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.54 |
| ▸ | CDC25B | P30305 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | MAP2K7 | O14733 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NSD2 | O96028 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CDC25A | P30304 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | GNG2 | P59768 | 2/20 | 0.53 |
| ▸ | GNB1 | P62873 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19382541 | 0.88 | P2RY4 (0.69) | PLAURP2RY4P2RY12GNG2GNB1 | |
| SCHEMBL11172913 | 0.86 | P2RY4 (0.65) | P2RY4P2RY12ALDH1A1MAPK1GNG2 | |
| SCHEMBL11116594 | 0.84 | GNG2 (0.56) | PLAURP2RY4P2RY12ALDH1A1MAPK1 | |
| SCHEMBL13214014 | 0.84 | GNG2 (0.76) | P2RY4P2RY12ALDH1A1MAPK1GNG2 | |
| SCHEMBL10815044 | 0.84 | GNG2 (0.68) | P2RY4P2RY12ALDH1A1MAPK1GNG2 | |
| SCHEMBL3033166 | 0.83 | GNG2 (0.74) | P2RY4P2RY12ALDH1A1MAPK1GNG2 | |
| SCHEMBL3033165 | 0.82 | P2RY4 (0.80) | P2RY4P2RY12MEN1KMT2ACDK2 | |
| SCHEMBL11120841 | 0.79 | P2RY4 (0.68) | P2RY4P2RY12GNG2GNB1PHLPP2 | |
| SCHEMBL11290029 | 0.79 | MEN1 (0.67) | PLAURMAPK1MEN1MAPTKMT2A | |
| SCHEMBL10794537 | 0.79 | CDC25B (0.61) | PLAURCDC25BALDH1A1MAPK1MAP2K7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10550090-B2 | Process for preparing substituted 9,10-dioxo-9,10-dihydroanthrecenes and 6H-anthra[1,9-cd]isoxazol-6-ones | PURDUE PHARMA L.P. (US) | 2020-02-04 | — | — | US | disclosed |
| US-20190084942-A1 | PROCESS FOR PREPARING SUBSTITUTED 9,10-DIOXO-9,10-DIHYDROANTHRECENES AND 6H-ANTHRA[1,9-CD]ISOXAZOL-6-ONES | PURDUE PHARMA L.P. | 2019-03-21 | — | — | US | disclosed |
| WO-2017161235-A1 | PROCESS FOR PREPARING SUBSTITUTED 9,10-DIOXO-9,10-DIOXO-9,10-DIHYDROANTHRECENES AND 6H-ANTHRA(1,9-CD)ISOXAZOL-6-ONES | PURDUE PHARMA L. P. (US) | 2017-09-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190084942-A1 | PROCESS FOR PREPARING SUBSTITUTED 9,10-DIOXO-9,10-DIHYDROANTHRECENES AND 6H-ANTHRA[1,9-CD]ISOXAZOL-6-ONES | ANTXR2, DHRS9, CYP2C9 | PLAUR 3448/4885P2RY4 463/4885P2RY12 840/4885 |
| US-10550090-B2 | Process for preparing substituted 9,10-dioxo-9,10-dihydroanthrecenes and 6H-anthra[1,9-cd]isoxazol-6-ones | ANTXR2, CYP2C9, DHRS9 | PLAUR 3395/4885P2RY4 435/4885P2RY12 790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.