Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 18/20 | 0.36 |
| ▸ | ITGB2 | P05107 | 17/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 17/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD4 | P21917 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22296987 | 0.90 | ITGAL (0.37) | ITGALITGB2ICAM1 | |
| SCHEMBL18868588 | 0.78 | ITGAL (0.39) | ITGALITGB2ICAM1 | |
| SCHEMBL13821870 | 0.73 | ITGAL (0.46) | ITGALITGB2ICAM1 | |
| SCHEMBL23176446 | 0.72 | ITGAL (0.48) | ITGALITGB2ICAM1 | |
| SCHEMBL18868608 | 0.71 | ITGAL (0.45) | ITGALITGB2ICAM1 | |
| SCHEMBL13894065 | 0.71 | ITGAL (0.48) | ITGALITGB2ICAM1 | |
| SCHEMBL18867977 | 0.71 | ITGAL (0.49) | ITGALITGB2ICAM1 | |
| SCHEMBL13894114 | 0.71 | ITGAL (0.48) | ITGALITGB2ICAM1 | |
| SCHEMBL23176604 | 0.70 | ITGAL (0.46) | ITGALITGB2ICAM1 | |
| SCHEMBL18868528 | 0.68 | ITGAL (0.40) | ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3797775-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF DIABETIC RETINOPATHY | Novartis AG (CH) | 2021-03-31 | — | — | EP | disclosed |
| EP-3167886-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF MACULAR EDEMA | SARcode Bioscience Inc. (US) | 2017-05-17 | — | — | EP | disclosed |