Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 1/20 | 0.40 |
| ▸ | KYNU | Q16719 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22296987 | 0.78 | ITGAL (0.37) | ITGAL | |
| SCHEMBL18868588 | 0.77 | ITGAL (0.39) | ITGAL | |
| SCHEMBL18868626 | 0.69 | ITGAL (0.53) | ITGALKYNUOPRK1ADRB3ADRB1 | |
| SCHEMBL18867996 | 0.68 | ITGAL (0.53) | ITGALKYNUOPRK1ADRB3ADRB1 | |
| SCHEMBL18868108 | 0.68 | ITGAL (0.36) | ITGAL | |
| SCHEMBL23176604 | 0.68 | ITGAL (0.46) | ITGAL | |
| SCHEMBL18868542 | 0.68 | ITGAL (0.54) | ITGALKYNUOPRK1ADRB3ADRB1 | |
| SCHEMBL10112626 | 0.67 | ITGAL (0.65) | ITGALKYNUOPRK1ADRB3ADRB1 | |
| SCHEMBL18867719 | 0.64 | ITGAL (0.59) | ITGALKYNUOPRK1ADRB3ADRB1 | |
| SCHEMBL12188990 | 0.63 | ITGAL (0.64) | ITGALKYNUOPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3797775-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF DIABETIC RETINOPATHY | Novartis AG (CH) | 2021-03-31 | — | — | EP | disclosed |
| EP-3167886-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF MACULAR EDEMA | SARcode Bioscience Inc. (US) | 2017-05-17 | — | — | EP | disclosed |