Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 1/20 | 0.54 |
| ▸ | KYNU | Q16719 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.31 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18868626 | 0.88 | ITGAL (0.53) | ITGALKYNUOPRK1ITGB1ITGA4 | |
| SCHEMBL10112626 | 0.82 | ITGAL (0.65) | ITGALKYNUOPRK1ITGB1ITGA4 | |
| SCHEMBL18883796 | 0.82 | ITGAL (0.61) | ITGALKYNUOPRK1ITGB1ITGA4 | |
| SCHEMBL23153599 | 0.81 | ITGAL (0.64) | ITGALKYNUOPRK1ITGB1ITGA4 | |
| SCHEMBL22296845 | 0.80 | ITGAL (0.64) | ITGALKYNUOPRK1ITGB1ITGA4 | |
| SCHEMBL18867996 | 0.80 | ITGAL (0.53) | ITGALKYNUOPRK1ITGB1ADRB1 | |
| SCHEMBL4926853 | 0.80 | ITGAL (0.63) | ITGALKYNUOPRK1ITGB1ITGA4 | |
| SCHEMBL13894422 | 0.80 | ITGAL (0.65) | ITGALOPRK1ITGB1ITGA4SLC16A3 | |
| SCHEMBL19157785 | 0.80 | ITGAL (0.63) | ITGALKYNUOPRK1ITGB1ITGA4 | |
| SCHEMBL19158608 | 0.79 | ITGAL (0.62) | ITGALKYNUOPRK1ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3167886-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF MACULAR EDEMA | SARcode Bioscience Inc. (US) | 2017-05-17 | — | — | EP | disclosed |