Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 11/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.55 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4389431 | 0.91 | ELANE (0.74) | ELANEALDH1A1SRD5A2MEN1NPC1 | |
| SCHEMBL16721011 | 0.89 | ELANE (0.71) | ELANEALDH1A1SRD5A2MEN1NPC1 | |
| SCHEMBL97469 | 0.87 | USP2 (0.60) | ELANELMNAALDH1A1USP2CES2 | |
| SCHEMBL6425454 | 0.85 | SRD5A2 (0.67) | ELANELMNAALDH1A1SRD5A2CES2 | |
| Benzophenone SCHEMBL16721021 | 0.85 | ELANE (0.64) | ELANEALDH1A1SRD5A2MEN1NPC1 | |
| Benzophenone SCHEMBL5162782 | 0.84 | ALDH1A1 (0.80) | ELANELMNAALDH1A1SRD5A2CES2 | |
| SCHEMBL259065 | 0.84 | ALDH1A1 (0.80) | ELANELMNAALDH1A1SRD5A2CES2 | |
| SCHEMBL235 | 0.84 | ALDH1A1 (0.80) | ELANELMNAALDH1A1SRD5A2CES2 | |
| SCHEMBL10877169 | 0.84 | ALDH1A1 (0.80) | ELANELMNAALDH1A1SRD5A2CES2 | |
| SCHEMBL1598717 | 0.84 | ELANE (0.70) | ELANELMNAALDH1A1SRD5A2CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2935398-B1 | BLENDS CONTAINING PHOTOACTIVE ADDITIVES | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2017-05-17 | — | — | EP | disclosed |