SCHEMBL820309

SCHEMBL820309

CCCCCCCCNCCNC

nearest known ligand 0.70

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 4/20 0.70
TSHR P16473 3/20 0.68
ALDH1A1 P00352 1/20 0.68
S1PR2 O95136 7/20 0.59
S1PR1 P21453 7/20 0.59
S1PR3 Q99500 7/20 0.59
S1PR4 O95977 6/20 0.59
S1PR5 Q9H228 1/20 0.59
ADH1B P00325 1/20 0.48
ADH1C P00326 1/20 0.48
ADH1A P07327 1/20 0.48
ADH4 P08319 1/20 0.48
ADH7 P40394 1/20 0.48
CYP1A2 P05177 1/20 0.43
CYP2C19 P33261 1/20 0.43
THRB P10828 1/20 0.42
SIGMAR1 Q99720 1/20 0.42
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25553994 1.00 EPHX1 (0.70) EPHX1TSHRALDH1A1S1PR2S1PR1
SCHEMBL17480037 1.00 EPHX1 (0.70) EPHX1TSHRALDH1A1S1PR2S1PR1
SCHEMBL17480035 1.00 EPHX1 (0.70) EPHX1TSHRALDH1A1S1PR2S1PR1
SCHEMBL17480032 1.00 EPHX1 (0.70) EPHX1TSHRALDH1A1S1PR2S1PR1
SCHEMBL6892698 1.00 EPHX1 (0.70) EPHX1TSHRALDH1A1S1PR2S1PR1
SCHEMBL24042526 1.00 EPHX1 (0.70) EPHX1TSHRALDH1A1S1PR2S1PR1
SCHEMBL11974145 1.00 EPHX1 (0.70) EPHX1TSHRALDH1A1S1PR2S1PR1
SCHEMBL17480033 1.00 EPHX1 (0.70) EPHX1TSHRALDH1A1S1PR2S1PR1
SCHEMBL6888368 1.00 EPHX1 (0.70) EPHX1TSHRALDH1A1S1PR2S1PR1
SCHEMBL17480034 1.00 EPHX1 (0.70) EPHX1TSHRALDH1A1S1PR2S1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1533293-B1 Preparation of functional monomers for grafting to low molecular weight polyalkenes and their use in the preparation of dispersants and lubricating oil compositions containing dispersant polyalkenes CASTROL LTD (GB) 2009-08-19 EP claimed
WO-2024049979-A2 NOVEL IONIZABLE LIPIDS AND LIPID NANOPARTICLES AND METHODS OF USING THE SAME SENDA BIOSCIENCES, INC. (US) 2024-03-07 WO disclosed
WO-2020127389-A1 LUBRICATING COMPOSITIONS COMPRISING CARBOXYLIC ACID SALT ADDITIVE, USES AND METHODS OF PREPARING CASTROL LIMITED (GB) 2020-06-25 WO disclosed
US-10190070-B2 Multiple-function dispersant graft polymer CASTROL LIMITED (GB) 2019-01-29 US disclosed
US-8703873-B2 Multiple function graft polymer CASTROL LIMITED (GB) 2014-04-22 US disclosed
EP-1513794-B1 PREPARATION OF MONOMERS FOR GRAFTING TO POLYOLEFINS, AND LUBRICATING OIL COMPOSITIONS CONTAINING GRAFTED COPOLYMER CASTROL LTD (GB) 2013-03-06 EP disclosed
EP-2552977-A1 MULTIPLE FUNCTION GRAFT POLYMER Castrol Limited (GB) 2013-02-06 EP disclosed
US-20120323018-A1 Preparation of Monomers for Grafting to Polyolefins, and Lubricating Oil Compositions Containing Grafted Copolymer GOLDBLATT IRWIN L (US) 2012-12-20 US disclosed
US-8283407-B2 Innerlining for tires; elastomer moodified with anhydride EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-10-09 US disclosed
EP-2501726-A1 MULTIFUNCTIONAL MULTIPLE GRAFT MONOMER LOW MOLECULAR WEIGHT POLYMER Castrol Limited (GB) 2012-09-26 EP disclosed
EP-0066953-B1 ETHYLENE COPOLYMER VISCOSITY INDEX IMPROVER-DISPERSANT ADDITIVE USEFUL IN OIL COMPOSITIONS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1986-11-12 EP disclosed
US-4557847-A POLYMER REACTION PRODUCT WITH POLYAMINE AND MONO ACID EXXON RESEARCH & ENGINEERING CO. (US) 1985-12-10 US disclosed
EP-0146162-A2 Preparation of ethylene copolymer viscosity index improver - dispersant additive useful in oil compositions EXXON RESEARCH AND ENGINEERING COMPANY (US) 1985-06-26 EP disclosed
EP-0145369-A2 Ethylene copolymer viscosity index improver - dispersant additive useful in oil compositions EXXON RESEARCH AND ENGINEERING COMPANY (US) 1985-06-19 EP disclosed
US-4517104-A POLYAMINE, MALEIC ANHYDRIDE, SUCCINIC ACID OR ANHYDRIDE MODIFIED POLYOLEFIN EXXON RESEARCH & ENGINEERING CO. (US) 1985-05-14 US disclosed
EP-0066953-A2 Ethylene copolymer viscosity index improver-dispersant additive useful in oil compositions EXXON RESEARCH AND ENGINEERING COMPANY (US) 1982-12-15 EP disclosed
US-4328003-A Alcohol fuels of decreased corrosivity EXXON RESEARCH & ENGINEERING CO. (US) 1982-05-04 US disclosed
US-4303539-A OR FUEL ADDITIVES COMPRISING A POLYISOBUTENYL ISOTHIOCYANATE EXXON RESEARCH & ENGINEERING CO. (US) 1981-12-01 US disclosed
US-4105571-A ZINC DIHYDROCARBYL DITHIOPHOSPHATE, ESTER OF A POLYCARBOXYLIC ACID AND A GLYCOL, ASHLESS DISPERSANT EXXON RESEARCH & ENGINEERING CO. (US) 1978-08-08 US disclosed
US-3948800-A Dispersant compositions THE LUBRIZOL CORPORATION (US) 1976-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120323018-A1 Preparation of Monomers for Grafting to Polyolefins, and Lubricating Oil Compositions Containing Grafted Copolymer ALOX5, ACMSD, F12 EPHX1 887/4885TSHR 4759/4885ALDH1A1 584/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.