Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.33 |
| ▸ | DRD3 | P35462 | 9/20 | 0.33 |
| ▸ | HTR1D | P28221 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 7/20 | 0.32 |
| ▸ | DRD1 | P21728 | 5/20 | 0.32 |
| ▸ | DRD5 | P21918 | 5/20 | 0.32 |
| ▸ | HTR5A | P47898 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17019699 | 0.89 | DRD2 (0.40) | DRD2DRD3HTR1DDRD4DRD1 | |
| SCHEMBL17014435 | 0.87 | — | — | |
| SCHEMBL17019619 | 0.87 | DRD2 (0.40) | DRD2DRD3HTR1DDRD4DRD1 | |
| SCHEMBL17019663 | 0.84 | DRD2 (0.40) | DRD2DRD3HTR1DDRD4DRD1 | |
| SCHEMBL17014441 | 0.83 | MEN1 (0.32) | DRD2DRD3HTR1DDRD4DRD1 | |
| SCHEMBL17014436 | 0.82 | DRD2 (0.33) | DRD2DRD3HTR1DDRD4DRD1 | |
| SCHEMBL17014405 | 0.82 | DRD2 (0.36) | DRD2DRD3HTR1DDRD4DRD1 | |
| SCHEMBL17019626 | 0.81 | HSD11B1 (0.36) | DRD2DRD3HTR1DDRD4DRD1 | |
| SCHEMBL17014449 | 0.80 | DRD2 (0.39) | DRD2DRD3HTR1DDRD4DRD1 | |
| SCHEMBL17014326 | 0.77 | DRD2 (0.39) | DRD2DRD3HTR1DDRD4DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900656-B1 | SPIRO RING COMPOUNDS AS HEPATITIS C VIRUS (HCV) INHIBITORS | SUNSHINE LAKE PHARMA CO LTD (CN) | 2017-05-17 | — | — | EP | disclosed |