Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.39 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1405487 | 0.72 | TSHR (0.67) | KMT2AMAPTMEN1ALDH1A1MAPK1 | |
| SCHEMBL1405486 | 0.72 | TSHR (0.67) | KMT2AMAPTMEN1ALDH1A1MAPK1 | |
| SCHEMBL14280247 | 0.72 | KMT2A (0.45) | KMT2AMAPTMEN1ALDH1A1MAPK1 | |
| SCHEMBL13640183 | 0.72 | MAPT (0.51) | KMT2AMAPTMEN1ALDH1A1MAPK1 | |
| SCHEMBL14280239 | 0.72 | KMT2A (0.44) | KMT2AMAPTMEN1ALDH1A1MAPK1 | |
| SCHEMBL18871441 | 0.72 | ALDH1A1 (0.50) | KMT2AMAPTMEN1ALDH1A1NPC1 | |
| SCHEMBL18870971 | 0.72 | TSHR (0.50) | KMT2AMAPTMEN1ALDH1A1NPC1 | |
| SCHEMBL1405403 | 0.68 | NPC1 (0.65) | KMT2AMAPTMEN1ALDH1A1MAPK1 | |
| SCHEMBL1405402 | 0.68 | NPC1 (0.65) | KMT2AMAPTMEN1ALDH1A1MAPK1 | |
| SCHEMBL18871494 | 0.68 | ALDH1A1 (0.36) | KMT2AMAPTMEN1ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2477491-B1 | PLANT ADDITIVES AND USES THEREOF TO MODULATE THE SYNTHESIS OF MEMBRANE GLYCEROLIPIDS IN PLANTS | COMMISSARIAT L ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES (FR) | 2017-05-17 | — | — | EP | disclosed |