SCHEMBL18873151

SCHEMBL18873151

CNC(=O)C1CCC(C(=O)O)CC2CC(C1)C(=O)OC2=O

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.39
AKR1C1 Q04828 1/20 0.39
CHRNB2 P17787 2/20 0.34
CHRNA4 P43681 2/20 0.34
CHRNA7 P36544 1/20 0.34
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
PDE4A P27815 1/20 0.33
PDE4B Q07343 1/20 0.33
PDE4C Q08493 1/20 0.33
PDE4D Q08499 1/20 0.33
ALDH1A1 P00352 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ACE P12821 1/20 0.30
USP2 O75604 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16265065 0.91 AKR1C3 (0.39) AKR1C3AKR1C1CHRNB2CHRNA4CHRNA7
SCHEMBL19301946 0.84 USP2 (0.33) AKR1C3AKR1C1CHRNB2CHRNA4CHRNA7
SCHEMBL1472153 0.79 AKR1C3 (0.38) AKR1C3AKR1C1ALOX15
Hydrochloric Acid SCHEMBL5856466 0.77 AKR1C3 (0.37) AKR1C3AKR1C1ALOX15
SCHEMBL2160521 0.72 BTK (0.45) CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3
SCHEMBL12563704 0.71 CHRNB2 (0.43) CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3
SCHEMBL19301951 0.69 HDAC8 (0.42) CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3
SCHEMBL5856453 0.68
SCHEMBL4588796 0.68 AKR1C3 (0.67) AKR1C3AKR1C1PDE4APDE4BPDE4C
SCHEMBL17950962 0.67 CHRNB2 (0.54) CHRNB2CHRNA4CHRNA7CHRNB4CHRNA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9649791-B2 Optical film and method of preparing optical film SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-05-16 US disclosed