Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 15/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28749297 | 0.75 | — | — | |
| SCHEMBL1243386 | 0.73 | GRM5 (0.56) | GRM5CYP1A2CYP2D6 | |
| SCHEMBL19154597 | 0.73 | GRM5 (0.71) | GRM5 | |
| SCHEMBL3353813 | 0.71 | GRM5 (0.68) | GRM5CYP1A2CYP2D6 | |
| SCHEMBL15483095 | 0.71 | GRM5 (0.53) | GRM5CYP1A2CYP2D6 | |
| SCHEMBL4161912 | 0.71 | GRM5 (1.00) | GRM5 | |
| SCHEMBL1560740 | 0.70 | — | — | |
| SCHEMBL1118960 | 0.70 | — | — | |
| SCHEMBL1244046 | 0.70 | — | — | |
| SCHEMBL6024302 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49735-E1 | Oxazolidinones as modulators of MGLUR5 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-11-28 | — | — | US | disclosed |
| US-10287220-B2 | Fluorination method | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2019-05-14 | — | — | US | disclosed |
| US-20170137341-A1 | FLUORINATION METHOD | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2017-05-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10287220-B2 | Fluorination method | F13B, PPARG, PGC | GRM5 950/4885CYP1A2 316/4885CYP2D6 551/4885 |
| US-20170137341-A1 | FLUORINATION METHOD | F13B, PPARG, PGC | GRM5 972/4885CYP1A2 318/4885CYP2D6 578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.