Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 19/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4154176 | 0.82 | GRM5 (1.00) | GRM5CYP1A2CYP2D6 | |
| SCHEMBL15483095 | 0.81 | GRM5 (0.53) | GRM5CYP1A2CYP2D6 | |
| SCHEMBL3346786 | 0.74 | GRM5 (0.42) | GRM5 | |
| SCHEMBL5567321 | 0.74 | GRM5 (0.46) | GRM5CYP1A2CYP2D6 | |
| SCHEMBL28749297 | 0.74 | — | — | |
| SCHEMBL1244046 | 0.73 | — | — | |
| SCHEMBL1243386 | 0.72 | GRM5 (0.56) | GRM5CYP1A2CYP2D6 | |
| SCHEMBL102265 | 0.72 | GRM5 (0.60) | GRM5CYP1A2CYP2D6 | |
| SCHEMBL18873238 | 0.71 | GRM5 (0.54) | GRM5CYP1A2CYP2D6 | |
| SCHEMBL6750170 | 0.69 | GRM5 (0.39) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010063487-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2010-06-10 | — | — | WO | disclosed |