Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 11/20 | 0.47 |
| ▸ | TK2 | O00142 | 7/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.44 |
| ▸ | TK1 | P04183 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1885698 | 1.00 | LTB4R (0.47) | LTB4RTK2KIF11TK1 | |
| SCHEMBL17377658 | 0.86 | KIF11 (0.47) | TK2KIF11TK1 | |
| SCHEMBL8972396 | 0.83 | KIF11 (0.47) | TK2KIF11TK1 | |
| SCHEMBL3016342 | 0.80 | TK2 (0.43) | TK2KIF11TK1 | |
| SCHEMBL9365537 | 0.78 | KIF11 (0.43) | KIF11TK1 | |
| SCHEMBL9365526 | 0.78 | KIF11 (0.43) | KIF11TK1 | |
| SCHEMBL29713494 | 0.78 | KIF11 (0.45) | TK2KIF11TK1 | |
| SCHEMBL30825832 | 0.77 | KIF11 (0.47) | TK2KIF11TK1 | |
| SCHEMBL2835140 | 0.77 | KIF11 (0.53) | LTB4RKIF11 | |
| SCHEMBL1884316 | 0.76 | KIF11 (0.50) | LTB4RTK2KIF11TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8623326-B2 | Ghrelin analogues | UNIVERSITY OF WESTERN ONTARIO (CA) | 2014-01-07 | — | — | US | disclosed |
| US-20110110855-A1 | NOVEL GHRELIN ANALOGUES | THE UNIVERSITY OF WESTERN ONTARIO (CA) | 2011-05-12 | — | — | US | disclosed |
| WO-2009140763-A1 | NOVEL GHRELIN ANALOGUES | THE UNIVERSITY OF WESTERN ONTARIO (CA) | 2009-11-26 | — | — | WO | disclosed |