Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 5/20 | 0.56 |
| ▸ | C5AR1 | P21730 | 4/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18874036 | 0.93 | LPAR1 (0.56) | LPAR1C5AR1SIRT2CXCR5 | |
| SCHEMBL18874205 | 0.92 | LPAR1 (0.56) | LPAR1C5AR1SIRT2FFAR4 | |
| SCHEMBL18874189 | 0.89 | LPAR1 (0.58) | LPAR1C5AR1SIRT2CHRM5CHRM1 | |
| SCHEMBL18874199 | 0.88 | LPAR1 (0.57) | LPAR1C5AR1SIRT2CHRM5CHRM1 | |
| SCHEMBL18874159 | 0.88 | LPAR1 (0.57) | LPAR1C5AR1SIRT2CHRM5CHRM1 | |
| SCHEMBL18873905 | 0.88 | LPAR1 (0.57) | LPAR1C5AR1SIRT2CHRM5CHRM1 | |
| SCHEMBL18874171 | 0.87 | LPAR1 (0.55) | LPAR1C5AR1SIRT2MCHR1CXCR5 | |
| SCHEMBL18873898 | 0.86 | LPAR1 (0.56) | LPAR1SIRT2CHRM5CHRM1CXCR5 | |
| SCHEMBL18873861 | 0.86 | LPAR1 (0.75) | LPAR1C5AR1SIRT2CHRM5CHRM1 | |
| SCHEMBL18874045 | 0.86 | LPAR1 (0.56) | LPAR1SIRT2CHRM5CHRM1CXCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303270-B1 | ACYLAMINO-SUBSTITUTED FUSED CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-17 | — | — | EP | disclosed |