Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 5/20 | 0.56 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | CXCR5 | P32302 | 5/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18874189 | 0.88 | LPAR1 (0.58) | LPAR1SIRT2CXCR5NPC1RAB9A | |
| SCHEMBL18874159 | 0.87 | LPAR1 (0.57) | LPAR1SIRT2CXCR5NPC1RAB9A | |
| SCHEMBL18873905 | 0.87 | LPAR1 (0.57) | LPAR1SIRT2CXCR5NPC1RAB9A | |
| SCHEMBL18874199 | 0.87 | LPAR1 (0.57) | LPAR1SIRT2CXCR5NPC1RAB9A | |
| SCHEMBL18873882 | 0.86 | LPAR1 (0.56) | LPAR1SIRT2CXCR5CHRM5CHRM1 | |
| SCHEMBL18874036 | 0.86 | LPAR1 (0.56) | LPAR1SIRT2CXCR5POLBMEN1 | |
| SCHEMBL18874205 | 0.85 | LPAR1 (0.56) | LPAR1SIRT2 | |
| SCHEMBL18873861 | 0.85 | LPAR1 (0.75) | LPAR1SIRT2CXCR5NPC1RAB9A | |
| SCHEMBL18873898 | 0.85 | LPAR1 (0.56) | LPAR1SIRT2CXCR5CHRM5CHRM1 | |
| SCHEMBL18874171 | 0.85 | LPAR1 (0.55) | LPAR1SIRT2CXCR5MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303270-B1 | ACYLAMINO-SUBSTITUTED FUSED CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-17 | — | — | EP | disclosed |