Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 6/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1561628 | 0.86 | LPAR1 (0.58) | LPAR1 | |
| SCHEMBL1560511 | 0.81 | LPAR1 (0.60) | LPAR1 | |
| SCHEMBL1561271 | 0.80 | LPAR1 (0.73) | LPAR1POLBMAPT | |
| SCHEMBL1561309 | 0.77 | LPAR1 (0.55) | LPAR1POLBPKMMEN1KMT2A | |
| SCHEMBL1988472 | 0.75 | LPAR1 (0.49) | LPAR1POLBPKMMEN1KMT2A | |
| SCHEMBL18874417 | 0.75 | POLB (0.46) | LPAR1POLBPKMMEN1KMT2A | |
| SCHEMBL18874043 | 0.75 | LPAR1 (0.48) | LPAR1POLBSIGMAR1 | |
| SCHEMBL18874186 | 0.74 | LPAR1 (0.49) | LPAR1POLBSIGMAR1 | |
| SCHEMBL18874338 | 0.74 | LPAR1 (0.47) | LPAR1POLBSIGMAR1 | |
| SCHEMBL18087510 | 0.73 | LPAR1 (0.60) | LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303270-B1 | ACYLAMINO-SUBSTITUTED FUSED CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-17 | — | — | EP | disclosed |