Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CXCR5 | P32302 | 8/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1561596 | 0.85 | LPAR1 (0.57) | LPAR1CXCR5 | |
| SCHEMBL18874194 | 0.81 | LPAR1 (0.60) | LPAR1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL18874159 | 0.75 | LPAR1 (0.57) | LPAR1CXCR5SIRT2 | |
| SCHEMBL18874189 | 0.74 | LPAR1 (0.58) | LPAR1KMT2AMEN1CXCR5SIRT2 | |
| SCHEMBL18873898 | 0.74 | LPAR1 (0.56) | LPAR1KMT2AMEN1CXCR5SIRT2 | |
| SCHEMBL18874199 | 0.73 | LPAR1 (0.57) | LPAR1CXCR5SIRT2ALDH1A1 | |
| SCHEMBL18874055 | 0.73 | NAMPT (0.38) | MAPTCXCR5ALDH1A1NAMPT | |
| SCHEMBL18874410 | 0.73 | LPAR1 (0.55) | LMNALPAR1KMT2AMAPTCXCR5 | |
| SCHEMBL18874187 | 0.72 | LPAR1 (0.44) | LPAR1KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL18874338 | 0.72 | LPAR1 (0.47) | LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303270-B1 | ACYLAMINO-SUBSTITUTED FUSED CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-17 | — | — | EP | disclosed |