Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MPI | P34949 | 1/20 | 0.43 |
| ▸ | F10 | P00742 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1561337 | 0.86 | LPAR1 (0.78) | LPAR1MPIF10 | |
| SCHEMBL18874315 | 0.81 | LMNA (0.42) | LPAR1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL18874338 | 0.80 | LPAR1 (0.47) | LPAR1NPC1RAB9A | |
| SCHEMBL18874210 | 0.80 | MPI (0.41) | LPAR1MPIF10GRM4 | |
| SCHEMBL18874043 | 0.79 | LPAR1 (0.48) | LPAR1NPC1RAB9A | |
| SCHEMBL1561323 | 0.79 | LPAR1 (0.67) | LPAR1F10 | |
| SCHEMBL18874186 | 0.78 | LPAR1 (0.49) | LPAR1NPC1RAB9A | |
| SCHEMBL18873947 | 0.78 | LPAR1 (0.47) | LPAR1KMT2ANPC1RAB9A | |
| SCHEMBL18874173 | 0.77 | LPAR1 (0.46) | LPAR1NPC1RAB9A | |
| SCHEMBL18874419 | 0.77 | HPGD (0.39) | LPAR1KDM4EALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303270-B1 | ACYLAMINO-SUBSTITUTED FUSED CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-17 | — | — | EP | disclosed |