Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | CXCR5 | P32302 | 3/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.32 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1561300 | 0.85 | CXCR5 (0.42) | NAMPTHIF1AHTR2ACXCR5NPC1 | |
| SCHEMBL18874315 | 0.73 | LMNA (0.42) | NAMPTMAPTCXCR5ALDH1A1 | |
| SCHEMBL1561717 | 0.67 | LPAR1 (0.56) | CXCR5NPC1RAB9A | |
| SCHEMBL18874194 | 0.62 | LPAR1 (0.60) | ALDH1A1NPC1RAB9AGRM4 | |
| SCHEMBL3903026 | 0.62 | TAAR1 (0.62) | MAPTCNR1ALDH1A1GPR84CYP2D6 | |
| SCHEMBL22769148 | 0.61 | IDO1 (0.47) | ALDH1A1AR | |
| SCHEMBL18874332 | 0.60 | CXCR5 (0.39) | MAPTCXCR5ALDH1A1RAB9A | |
| SCHEMBL18874051 | 0.59 | KMT2A (0.58) | MAPTALDH1A1RAB9A | |
| SCHEMBL18874328 | 0.59 | CXCR5 (0.47) | HTR2AMAPTCXCR5ALDH1A1NPC1 | |
| SCHEMBL18873897 | 0.59 | KDM4E (0.47) | NAMPTHTR2ACXCR5ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2303270-B1 | ACYLAMINO-SUBSTITUTED FUSED CYCLOPENTANECARBOXYLIC ACID DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | SANOFI SA (FR) | 2017-05-17 | — | — | EP | disclosed |