Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | CCNC | P24863 | 2/20 | 0.37 |
| ▸ | CDK8 | P49336 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18874241 | 0.81 | KDM4E (0.42) | ALDH1A1MAPTKDM4EMAOBMEN1 | |
| SCHEMBL18873777 | 0.78 | ELANE (0.36) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL18873883 | 0.78 | KDM4E (0.35) | ALDH1A1MAPTKDM4EMEN1KMT2A | |
| SCHEMBL18874118 | 0.76 | — | — | |
| SCHEMBL18873804 | 0.72 | ALDH1A1 (0.38) | ALDH1A1MAPTKDM4EBRD4CYP2C9 | |
| SCHEMBL18874225 | 0.71 | ACACB (0.42) | MAPTMAOBMIFTP53 | |
| SCHEMBL18874381 | 0.70 | BRD4 (0.37) | ERAP1ALDH1A1MAPTKDM4ECCNC | |
| SCHEMBL12101783 | 0.67 | ALDH1A1 (0.36) | ERAP1ALDH1A1MAPTKDM4ECCNC | |
| SCHEMBL812202 | 0.66 | BRD4 (0.36) | ALDH1A1MAPTBRD4MEN1KMT2A | |
| SCHEMBL12101809 | 0.65 | HDAC4 (0.36) | ALDH1A1MAPTBRD4ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173755-B1 | NOVEL HERBICIDES | SYNGENTA LTD (GB) | 2017-05-17 | — | — | EP | disclosed |