Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | BRD2 | P25440 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18874241 | 0.81 | KDM4E (0.42) | ALDH1A1KMT2AMEN1POLBMAPT | |
| SCHEMBL18873777 | 0.78 | ELANE (0.36) | ALDH1A1KMT2AMEN1MAPTGAA | |
| SCHEMBL18873883 | 0.78 | KDM4E (0.35) | ALDH1A1KMT2AMEN1MAPTGAA | |
| SCHEMBL6727428 | 0.73 | ALDH1A1 (0.35) | ALDH1A1KMT2AMEN1POLBCYP2D6 | |
| SCHEMBL18873805 | 0.73 | ALDH1A1 (0.35) | ALDH1A1KMT2AMEN1POLBCYP2D6 | |
| SCHEMBL18874331 | 0.72 | ERAP1 (0.40) | ALDH1A1KMT2AMEN1CYP2C9CYP2C19 | |
| SCHEMBL18874005 | 0.63 | MAOB (0.40) | ALDH1A1KMT2APOLBTP53MAPT | |
| SCHEMBL1323891 | 0.59 | ALDH1A1 (0.60) | ALDH1A1KMT2AMEN1POLBCYP2D6 | |
| SCHEMBL23657488 | 0.59 | KMT2A (0.67) | ALDH1A1KMT2AMEN1TP53GAA | |
| SCHEMBL18874381 | 0.58 | BRD4 (0.37) | ALDH1A1CYP2C9CYP2C19TP53BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2173755-B1 | NOVEL HERBICIDES | SYNGENTA LTD (GB) | 2017-05-17 | — | — | EP | disclosed |