Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.41 |
| ▸ | RAB9A | P51151 | 7/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 5/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 5/20 | 0.41 |
| ▸ | RELA | Q04206 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | HPSE | Q9Y251 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18875246 | 1.00 | NPC1 (0.41) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL18875190 | 0.94 | NPC1 (0.46) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL18875201 | 0.91 | RAB9A (0.48) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL18875257 | 0.91 | TP53 (0.42) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL18875219 | 0.85 | TP53 (0.39) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL18875223 | 0.85 | TP53 (0.39) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL18875138 | 0.84 | RAB9A (0.54) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL18875160 | 0.83 | TP53 (0.48) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL18875300 | 0.82 | RAB9A (0.41) | NPC1RAB9ANFKB1NFKB2RELA | |
| SCHEMBL18875211 | 0.82 | KDM4E (0.34) | NPC1RAB9ANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170148996-A1 | ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC OPTOELECTRONIC DEVICES COMPRISING THE SAME | WUHAN TIANMA MICROELECTRONICS CO., LTD.SHANGHAI BRANCH (CN) | 2017-05-25 | — | — | US | disclosed |
| US-20170148996-A1 | ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC OPTOELECTRONIC DEVICES COMPRISING THE SAME | WUHAN TIANMA MICROELECTRONICS CO., LTD.SHANGHAI BRANCH (CN) | 2017-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170148996-A1 | ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC OPTOELECTRONIC DEVICES COMPRISING THE SAME | OR10J3, PPOX, OR51E2 | NPC1 3621/4885RAB9A 2603/4885NFKB1 4462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.