Sugi Predict

Sugi Predict / Compounds / SCHEMBL18877733

SCHEMBL18877733

SCHEMBL18877733

CC(C)(C)C1=CC(=CN=Nc2ccccc2Cl)C=C(C(C)(C)C)C1=O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 1/20 0.43
▸ GSK3B P49841 4/20 0.39
▸ MAPT P10636 5/20 0.37
▸ KMT2A Q03164 4/20 0.35
▸ NPC1 O15118 3/20 0.35
▸ ATM Q13315 1/20 0.35
▸ GPR35 Q9HC97 1/20 0.35
▸ MEN1 O00255 3/20 0.33
▸ HSD11B1 P28845 1/20 0.33
▸ GLA P06280 1/20 0.33
▸ CYP1A2 P05177 1/20 0.33
▸ ALDH1A1 P00352 2/20 0.33
▸ LMNA P02545 2/20 0.33
▸ TDP1 Q9NUW8 2/20 0.33
▸ L3MBTL1 Q9Y468 2/20 0.33
▸ POLB P06746 2/20 0.32
▸ RAB9A P51151 2/20 0.32
▸ NPSR1 Q6W5P4 1/20 0.32
▸ HPGD P15428 1/20 0.32
▸ GPR55 Q9Y2T6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18877773 0.92 GSK3B (0.36) SMN1; SMN2GSK3BMAPTKMT2AMEN1
SCHEMBL13580416 0.86 SMN1; SMN2 (0.44) SMN1; SMN2MAPTKMT2ANPC1ATM
SCHEMBL24543468 0.84 MAPT (0.35) SMN1; SMN2MAPTKMT2ANPC1ATM
SCHEMBL13580321 0.84 NPC1 (0.36) SMN1; SMN2KMT2ANPC1ATMGPR35
SCHEMBL18877730 0.84 KMT2A (0.36) SMN1; SMN2MAPTKMT2ANPC1ATM
SCHEMBL24543460 0.84 CTDSP1 (0.36) SMN1; SMN2MAPTKMT2ANPC1ATM
SCHEMBL18877740 0.83 SMN1; SMN2 (0.43) SMN1; SMN2KMT2ANPC1ATMGPR35
SCHEMBL18877741 0.83 SMN1; SMN2 (0.43) SMN1; SMN2MAPTKMT2ANPC1ATM
SCHEMBL14280240 0.81 SMN1; SMN2 (0.41) SMN1; SMN2MAPTKMT2ANPC1MEN1
SCHEMBL13580405 0.80 SMN1; SMN2 (0.32) SMN1; SMN2KMT2ANPC1ATMGPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10782622-B2 Photoreceptor for electrophotography, method for manufacturing the same, and electrophotographic device FUJI ELECTRIC CO., LTD. (JP) 2020-09-22 — — US disclosed
US-10747129-B2 Electrophotographic photoconductor, method of manufacturing the same, and electrophotographic apparatus FUJI ELECTRIC CO., LTD. (JP) 2020-08-18 — — US disclosed
US-20190346780-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, METHOD OF MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC APPARATUS FUJI ELECTRIC CO., LTD. (JP) 2019-11-14 — — US disclosed
US-20180024449-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, METHOD FOR MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2018-01-25 — — US disclosed
US-20180024449-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, METHOD FOR MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2018-01-25 — — US disclosed
US-9804511-B2 Electrophotographic photoreceptor, electrophotographic apparatus comprising the same, and package of electrophotographic photoreceptor FUJI ELECTRIC CO., LTD. (JP) 2017-10-31 — — US disclosed
US-9804511-B2 Electrophotographic photoreceptor, electrophotographic apparatus comprising the same, and package of electrophotographic photoreceptor FUJI ELECTRIC CO., LTD. (JP) 2017-10-31 — — US disclosed
US-20170146916-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC APPARATUS COMPRISING THE SAME, AND PACKAGE OF ELECTROPHOTOGRAPHIC PHOTORECEPTOR FUJI ELECTRIC CO., LTD. (JP) 2017-05-25 — — US disclosed
US-20170146916-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC APPARATUS COMPRISING THE SAME, AND PACKAGE OF ELECTROPHOTOGRAPHIC PHOTORECEPTOR FUJI ELECTRIC CO., LTD. (JP) 2017-05-25 — — US disclosed
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