Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 5/20 | 0.37 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.37 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14280268 | 0.84 | KMT2A (0.44) | KMT2AMEN1ACHENPC1RAB9A | |
| SCHEMBL14280242 | 0.84 | ALDH1A1 (0.40) | SMN1; SMN2KMT2AMEN1NPC1L3MBTL1 | |
| SCHEMBL13580416 | 0.83 | SMN1; SMN2 (0.44) | SMN1; SMN2KMT2AMEN1CES2CES1 | |
| SCHEMBL14306621 | 0.83 | ALDH1A1 (0.36) | SMN1; SMN2KMT2AMEN1NPC1MAPT | |
| SCHEMBL14280246 | 0.82 | ALDH1A1 (0.42) | SMN1; SMN2KMT2AMEN1PLAUCES2 | |
| SCHEMBL18877741 | 0.81 | SMN1; SMN2 (0.43) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL18877740 | 0.81 | SMN1; SMN2 (0.43) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL18877733 | 0.81 | SMN1; SMN2 (0.43) | SMN1; SMN2KMT2AMEN1NPC1RAB9A | |
| SCHEMBL14280243 | 0.80 | VCAM1 (0.41) | KMT2AMEN1NPC1RAB9AMAPT | |
| SCHEMBL13580425 | 0.79 | PTPRC (0.40) | KMT2AMEN1ACHECES1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7314692-B2 | Phenylazomethylene-cyclohexadienone derivatives comprising electron withdrawing group and electrophotographic photoreceptor comprising the derivatives | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2008-01-01 | — | — | US | disclosed |