SCHEMBL18877802

SCHEMBL18877802

CC1=CC(=CN=Nc2ccccc2)C=C(C(C)(C)C)C1=O

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 1/20 0.34
▸ NPC1 O15118 1/20 0.32
▸ KMT2A Q03164 1/20 0.32
▸ ATM Q13315 1/20 0.32
▸ GPR35 Q9HC97 1/20 0.32
▸ MAPT P10636 3/20 0.31
▸ POLB P06746 2/20 0.31
▸ GPR55 Q9Y2T6 1/20 0.31
▸ CYP2D6 P10635 1/20 0.31
▸ DDAH1 O94760 1/20 0.31
▸ LMNA P02545 2/20 0.30
▸ S1PR2 O95136 1/20 0.30
▸ ALDH1A1 P00352 1/20 0.30
▸ HSP90AA1 P07900 1/20 0.30
▸ XBP1 P17861 1/20 0.30
▸ MPI P34949 1/20 0.30
▸ OPRM1 P35372 1/20 0.30
▸ OPRD1 P41143 1/20 0.30
▸ RAB9A P51151 1/20 0.30
▸ NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21179846 0.91 SMN1; SMN2 (0.40) SMN1; SMN2NPC1KMT2AATMGPR35
SCHEMBL13986184 0.91 SMN1; SMN2 (0.40) SMN1; SMN2NPC1KMT2AATMGPR35
SCHEMBL18877771 0.89 NPC1 (0.32) SMN1; SMN2NPC1KMT2AATMGPR35
SCHEMBL13580451 0.87 NPC1 (0.32) NPC1KMT2AATMGPR35
SCHEMBL18877779 0.86 CYP2D6 (0.39) NPC1KMT2AATMGPR35CYP2D6
SCHEMBL18877804 0.86 PTGS1 (0.32) NPC1KMT2AATMGPR35
SCHEMBL18877799 0.86 MAPT (0.35) NPC1KMT2AATMGPR35MAPT
SCHEMBL18877800 0.85 KMT2A (0.36) NPC1KMT2AATMGPR35MAPT
SCHEMBL18877798 0.84 PTGS2 (0.40) SMN1; SMN2NPC1KMT2AATMGPR35
SCHEMBL18877801 0.84 MAPT (0.37) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10782622-B2 Photoreceptor for electrophotography, method for manufacturing the same, and electrophotographic device FUJI ELECTRIC CO., LTD. (JP) 2020-09-22 — — US disclosed
US-10747129-B2 Electrophotographic photoconductor, method of manufacturing the same, and electrophotographic apparatus FUJI ELECTRIC CO., LTD. (JP) 2020-08-18 — — US disclosed
US-20190346780-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, METHOD OF MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC APPARATUS FUJI ELECTRIC CO., LTD. (JP) 2019-11-14 — — US disclosed
US-20180024449-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, METHOD FOR MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2018-01-25 — — US disclosed
US-20180024449-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, METHOD FOR MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2018-01-25 — — US disclosed
US-9804511-B2 Electrophotographic photoreceptor, electrophotographic apparatus comprising the same, and package of electrophotographic photoreceptor FUJI ELECTRIC CO., LTD. (JP) 2017-10-31 — — US disclosed
US-9804511-B2 Electrophotographic photoreceptor, electrophotographic apparatus comprising the same, and package of electrophotographic photoreceptor FUJI ELECTRIC CO., LTD. (JP) 2017-10-31 — — US disclosed
US-20170146916-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC APPARATUS COMPRISING THE SAME, AND PACKAGE OF ELECTROPHOTOGRAPHIC PHOTORECEPTOR FUJI ELECTRIC CO., LTD. (JP) 2017-05-25 — — US disclosed
US-20170146916-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC APPARATUS COMPRISING THE SAME, AND PACKAGE OF ELECTROPHOTOGRAPHIC PHOTORECEPTOR FUJI ELECTRIC CO., LTD. (JP) 2017-05-25 — — US disclosed
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