SCHEMBL18877798

SCHEMBL18877798

COc1ccc(N=NC=C2C=C(C)C(=O)C(C(C)(C)C)=C2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PTGS2 P35354 3/20 0.40
▸ KMT2A Q03164 7/20 0.39
▸ MEN1 O00255 4/20 0.39
▸ ALDH1A1 P00352 3/20 0.39
▸ PKM P14618 2/20 0.39
▸ GAA P10253 1/20 0.39
▸ EP300 Q09472 1/20 0.38
▸ KAT2A Q92830 1/20 0.38
▸ KAT2B Q92831 1/20 0.38
▸ NPC1 O15118 4/20 0.37
▸ ATM Q13315 1/20 0.37
▸ GPR35 Q9HC97 1/20 0.37
▸ MAPT P10636 4/20 0.36
▸ RBBP9 O75884 1/20 0.34
▸ RAB9A P51151 3/20 0.33
▸ BRD4 O60885 1/20 0.33
▸ SMN1; SMN2 Q16637 1/20 0.33
▸ PTGS1 P23219 1/20 0.33
▸ GSK3B P49841 1/20 0.33
▸ CA12 O43570 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18877728 0.92 PTGS2 (0.43) PTGS2KMT2AMEN1ALDH1A1PKM
SCHEMBL18877771 0.87 NPC1 (0.32) PTGS2KMT2ANPC1ATMGPR35
SCHEMBL18877804 0.85 PTGS1 (0.32) PTGS2KMT2ANPC1ATMGPR35
SCHEMBL18877799 0.85 MAPT (0.35) KMT2AALDH1A1NPC1ATMGPR35
SCHEMBL18877779 0.85 CYP2D6 (0.39) KMT2ANPC1ATMGPR35
SCHEMBL18877802 0.84 SMN1; SMN2 (0.34) KMT2AALDH1A1NPC1ATMGPR35
SCHEMBL16215284 0.83 ATM (0.38) PTGS2KMT2AALDH1A1PKMNPC1
SCHEMBL15893571 0.83 ATM (0.38) PTGS2KMT2AALDH1A1PKMNPC1
SCHEMBL18877801 0.82 MAPT (0.37) PTGS2MAPTBRD4PTGS1
SCHEMBL18877782 0.81 BRD4 (0.34) KMT2ANPC1BRD4SMN1; SMN2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10782622-B2 Photoreceptor for electrophotography, method for manufacturing the same, and electrophotographic device FUJI ELECTRIC CO., LTD. (JP) 2020-09-22 — — US disclosed
US-10747129-B2 Electrophotographic photoconductor, method of manufacturing the same, and electrophotographic apparatus FUJI ELECTRIC CO., LTD. (JP) 2020-08-18 — — US disclosed
US-20190346780-A1 ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, METHOD OF MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC APPARATUS FUJI ELECTRIC CO., LTD. (JP) 2019-11-14 — — US disclosed
US-20180024449-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, METHOD FOR MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2018-01-25 — — US disclosed
US-20180024449-A1 PHOTORECEPTOR FOR ELECTROPHOTOGRAPHY, METHOD FOR MANUFACTURING THE SAME, AND ELECTROPHOTOGRAPHIC DEVICE FUJI ELECTRIC CO., LTD. (JP) 2018-01-25 — — US disclosed
US-9804511-B2 Electrophotographic photoreceptor, electrophotographic apparatus comprising the same, and package of electrophotographic photoreceptor FUJI ELECTRIC CO., LTD. (JP) 2017-10-31 — — US disclosed
US-9804511-B2 Electrophotographic photoreceptor, electrophotographic apparatus comprising the same, and package of electrophotographic photoreceptor FUJI ELECTRIC CO., LTD. (JP) 2017-10-31 — — US disclosed
US-20170146916-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC APPARATUS COMPRISING THE SAME, AND PACKAGE OF ELECTROPHOTOGRAPHIC PHOTORECEPTOR FUJI ELECTRIC CO., LTD. (JP) 2017-05-25 — — US disclosed
US-20170146916-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC APPARATUS COMPRISING THE SAME, AND PACKAGE OF ELECTROPHOTOGRAPHIC PHOTORECEPTOR FUJI ELECTRIC CO., LTD. (JP) 2017-05-25 — — US disclosed
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