SCHEMBL18878248

SCHEMBL18878248

c1ccc(-c2ccc(-c3nc(-c4ccccc4)nc(-c4cc(-c5cccc6ccccc56)cc(-c5cccc6ccccc56)c4)n3)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.53
ALDH1A1 P00352 4/20 0.53
HPGD P15428 4/20 0.53
KDM4E B2RXH2 3/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
MAPK1 P28482 2/20 0.53
HSD17B10 Q99714 2/20 0.53
ATM Q13315 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
TP53 P04637 1/20 0.53
TSHR P16473 1/20 0.53
NFKB1 P19838 1/20 0.53
NFKB2 Q00653 1/20 0.53
RELA Q04206 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
CA12 O43570 2/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
CA9 Q16790 2/20 0.48
MCL1 Q07820 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18878247 1.00 MAPT (0.53) MAPTALDH1A1HPGDKDM4ESMN1; SMN2
SCHEMBL18327634 0.98 MAPT (0.51) MAPTALDH1A1HPGDKDM4ESMN1; SMN2
SCHEMBL17932355 0.98 MAPT (0.51) MAPTALDH1A1HPGDKDM4ESMN1; SMN2
SCHEMBL17932420 0.97 ALDH1A1 (0.50) MAPTALDH1A1HPGDKDM4ESMN1; SMN2
SCHEMBL23370430 0.97 MAPT (0.53) MAPTALDH1A1HPGDKDM4ESMN1; SMN2
SCHEMBL18270339 0.97 MAPT (0.53) MAPTALDH1A1HPGDKDM4ESMN1; SMN2
SCHEMBL18270319 0.97 MAPT (0.53) MAPTALDH1A1HPGDKDM4ESMN1; SMN2
SCHEMBL17932316 0.97 MAPT (0.53) MAPTALDH1A1HPGDKDM4ESMN1; SMN2
SCHEMBL18270310 0.97 MAPT (0.53) MAPTALDH1A1HPGDKDM4ESMN1; SMN2
SCHEMBL18270347 0.97 MAPT (0.53) MAPTALDH1A1HPGDKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220407011-A1 ORGANIC COMPOUND, ORGANIC LIGHT-EMITTING DIODE INCLUDING ORGANIC COMPOUND, AND DISPLAY DEVICE INCLUDING ORGANIC LIGHT-EMITTING DIODE SOULBRAIN CO., LTD. (KR) 2022-12-22 US disclosed
US-11152576-B2 Organic light emitting device LG CHEM, LTD. (KR) 2021-10-19 US disclosed
WO-2021086142-A1 ORGANIC COMPOUND, ORGANIC LIGHT-EMITTING DIODE INCLUDING SAME, AND DISPLAY DEVICE INCLUDING ORGANIC LIGHT-EMITTING DIODE 솔브레인 주식회사 2021-05-06 WO disclosed
US-20210013422-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2021-01-14 US disclosed
EP-3174123-A1 ORGANIC LIGHT EMITTING DISPLAY DEVICE LG Display Co., Ltd. (KR) 2017-05-31 EP disclosed
US-20170148995-A1 ORGANIC LIGHT EMITTING DISPLAY DEVICE LG DISPLAY CO., LTD. (KR) 2017-05-25 US disclosed
US-20170148995-A1 ORGANIC LIGHT EMITTING DISPLAY DEVICE LG DISPLAY CO., LTD. (KR) 2017-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220407011-A1 ORGANIC COMPOUND, ORGANIC LIGHT-EMITTING DIODE INCLUDING ORGANIC COMPOUND, AND DISPLAY DEVICE INCLUDING ORGANIC LIGHT-EMITTING DIODE OCIAD1, AOX1, OXER1 MAPT 647/4885ALDH1A1 11/4885HPGD 2070/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.