Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 12/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 12/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 12/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MBOAT4 | Q96T53 | 2/20 | 0.33 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25163414 | 0.84 | RXRA (0.43) | RXRAGRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL21428809 | 0.81 | MEN1 (0.39) | RXRAGRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL30329185 | 0.81 | GAA (0.38) | RXRAGRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL17240893 | 0.80 | MKNK1 (0.36) | MEN1KMT2ACYP1A2CYP2C19LMNA | |
| SCHEMBL25164032 | 0.79 | MEN1 (0.43) | RXRAGRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL17240903 | 0.79 | MBOAT4 (0.37) | RXRAGRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL18878376 | 0.78 | CYP1A2 (0.51) | RXRAGRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL840990 | 0.76 | HPGD (0.46) | MEN1KMT2ACYP1A2CYP2C19LMNA | |
| SCHEMBL25164045 | 0.75 | RXRA (0.40) | RXRAGRIN1GRIN2BMEN1KMT2A | |
| SCHEMBL2251448 | 0.74 | RXRA (0.42) | RXRAGRIN1GRIN2BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9656970-B2 | 5-(trifluoromethyl)pyrimidine derivatives and method for producing same | TOSOH F-TECH, INC. (JP) | 2017-05-23 | — | — | US | disclosed |