SCHEMBL1887840

SCHEMBL1887840

CCc1cc(C(C)(C)C)cc(-c2c(-c3cc(C(C)(C)C)cc(CC)c3CC)c(-c3cc(C(C)(C)C)cc(CC)c3CC)c3c(c2-c2cc(C(C)(C)C)cc(CC)c2CC)=c2ccccc2=3)c1CC

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.35
CASP3 P42574 2/20 0.35
RAB9A P51151 2/20 0.35
SENP8 Q96LD8 2/20 0.35
SENP7 Q9BQF6 2/20 0.35
SENP6 Q9GZR1 2/20 0.35
ALDH1A1 P00352 1/20 0.35
PLA2G1B P04054 1/20 0.35
NFKB1 P19838 1/20 0.35
NFKB2 Q00653 1/20 0.35
RELA Q04206 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ATG4B Q9Y4P1 1/20 0.35
LMNA P02545 1/20 0.32
MAPK1 P28482 1/20 0.32
ATM Q13315 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2C19 P33261 1/20 0.31
CYP2D6 P10635 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1885181 0.85 NPC1 (0.35) NPC1CASP3RAB9ASENP8SENP7
SCHEMBL27771304 0.83 NPC1 (0.36) NPC1CASP3RAB9ASENP8SENP7
SCHEMBL1885743 0.80 TTR (0.33)
SCHEMBL27727072 0.76 RXRA (0.39)
SCHEMBL1893783 0.75 CYP1A2 (0.38) CYP1A2CYP2C19CYP2D6
SCHEMBL27727074 0.75 NPC1 (0.39) NPC1CASP3RAB9ASENP8SENP7
SCHEMBL1882864 0.73 NPC1 (0.36) NPC1CASP3RAB9ASENP8SENP7
SCHEMBL1888188 0.73 MEN1 (0.31)
SCHEMBL1886830 0.73 MEN1 (0.31)
SCHEMBL1888012 0.72 NPC1 (0.35) NPC1CASP3RAB9ASENP8SENP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7947342-B2 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2011-05-24 US disclosed
US-20100104879-A1 CLEAR HARD COAT FILM, ANTI-REFLECTION FILM, POLARIZING PLATE AND DISPLAY DEVICE EMPLOYING THE SAME KONICA MINOLTA OPTO, INC. (JP) 2010-04-29 US disclosed
EP-2012150-A1 POLARIZING PLATE PROTECTION FILM, METHOD FOR PRODUCING THE SAME, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY Konica Minolta Opto, Inc. (JP) 2009-01-07 EP disclosed
US-20070254115-A1 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2007-11-01 US disclosed