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SCHEMBL1893783

SCHEMBL1893783

CCc1cc(C(C)(C)C)cc(C(C)(C)C)c1-c1c(-c2c(CC)cc(C(C)(C)C)cc2C(C)(C)C)c(-c2c(CC)cc(C(C)(C)C)cc2C(C)(C)C)c2c(c1-c1c(CC)cc(C(C)(C)C)cc1C(C)(C)C)=c1ccccc1=2

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ CYP1A2 P05177 1/20 0.38
▸ CYP3A4 P08684 1/20 0.38
▸ CYP2C9 P11712 1/20 0.38
▸ TSHR P16473 1/20 0.38
▸ CYP2C19 P33261 1/20 0.38
▸ CYP2D6 P10635 1/20 0.31
▸ NR5A2 O00482 1/20 0.30
▸ NR5A1 Q13285 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL673853 0.85 TSHR (0.37) CYP1A2CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL27771301 0.83 CYP1A2 (0.35) CYP1A2CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL1884392 0.81 TSHR (0.35) CYP1A2CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL1885153 0.78 HSPA5 (0.41) CYP1A2TSHR
SCHEMBL27727062 0.77 CYP2C9 (0.41) CYP1A2CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL674906 0.75 — —
SCHEMBL1887840 0.75 NPC1 (0.35) CYP1A2CYP2C19CYP2D6
SCHEMBL27727063 0.75 CYP1A2 (0.40) CYP1A2CYP3A4CYP2C9TSHRCYP2C19
SCHEMBL1885181 0.75 NPC1 (0.35) CYP1A2CYP2C19CYP2D6
SCHEMBL1886102 0.72 GABRA1 (0.32) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7947342-B2 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2011-05-24 — — US disclosed
US-20100104879-A1 CLEAR HARD COAT FILM, ANTI-REFLECTION FILM, POLARIZING PLATE AND DISPLAY DEVICE EMPLOYING THE SAME KONICA MINOLTA OPTO, INC. (JP) 2010-04-29 — — US disclosed
EP-2012150-A1 POLARIZING PLATE PROTECTION FILM, METHOD FOR PRODUCING THE SAME, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY Konica Minolta Opto, Inc. (JP) 2009-01-07 — — EP disclosed
US-20070254115-A1 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2007-11-01 — — US disclosed