⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22698198 | 0.65 | — | — | |
| SCHEMBL210649 | 0.61 | — | — | |
| SCHEMBL18344086 | 0.61 | — | — | |
| SCHEMBL14665206 | 0.59 | — | — | |
| SCHEMBL5175554 | 0.59 | — | — | |
| SCHEMBL9557360 | 0.59 | LMNA (0.37) | — | |
| SCHEMBL12564705 | 0.59 | — | — | |
| SCHEMBL31123507 | 0.59 | — | — | |
| Hydrochloric Acid SCHEMBL20504419 | 0.59 | — | — | |
| SCHEMBL11813644 | 0.58 | PGK1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170145009-A1 | HETEROCYCLIC COMPOUNDS THAT INHIBIT THE KINASE ACTIVITY OF MNK USEFUL FOR TREATING VARIOUS CANCERS | EFFECTOR THERAPEUTICS, INC. | 2017-05-25 | — | — | US | disclosed |