Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 3/20 | 0.52 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.45 |
| ▸ | CTSK | P43235 | 3/20 | 0.45 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12637411 | 1.00 | TACR3 (0.52) | TACR3ENPEPCTSKAPAF1EPHX2 | |
| SCHEMBL23901642 | 0.85 | ENPEP (0.48) | TACR3ENPEPTRPA1MAPTALDH1A1 | |
| SCHEMBL12659224 | 0.80 | SMN1; SMN2 (0.47) | TACR3MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL12659236 | 0.80 | SMN1; SMN2 (0.47) | TACR3MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL12659222 | 0.80 | SMN1; SMN2 (0.47) | TACR3MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL12672526 | 0.80 | BLM (0.46) | TACR3APAF1MEN1KMT2AMAPT | |
| SCHEMBL12659226 | 0.80 | SMN1; SMN2 (0.47) | TACR3MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL16103900 | 0.77 | KMT2A (0.51) | TACR3MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL1888549 | 0.77 | KMT2A (0.51) | TACR3MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL1888547 | 0.77 | KMT2A (0.51) | TACR3MEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2050738-B1 | NOVEL IMIDAZOLIDINONE DERIVATIVE, METHOD OF PRODUCING THE SAME AND METHOD OF PRODUCING OPTICALLY ACTIVE AMINO ACID | KANEKA CORP (JP) | 2013-07-10 | — | — | EP | disclosed |
| US-7947722-B2 | Imidazolidinone derivative, method of producing the same and method of producing optically active amino acid | KANEKA CORPORATION (JP) | 2011-05-24 | — | — | US | disclosed |
| US-20090209768-A1 | NOVEL IMIDAZOLIDINONE DERIVATIVE, METHOD OF PRODUCING THE SAME AND METHOD OF PRODUCING OPTICALLY ACTIVE AMINO ACID | KANEKA CORPORATION (JP) | 2009-08-20 | — | — | US | disclosed |
| EP-2050738-A1 | NOVEL IMIDAZOLIDINONE DERIVATIVE, METHOD OF PRODUCING THE SAME AND METHOD OF PRODUCING OPTICALLY ACTIVE AMINO ACID | Kaneka Corporation (JP) | 2009-04-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090209768-A1 | NOVEL IMIDAZOLIDINONE DERIVATIVE, METHOD OF PRODUCING THE SAME AND METHOD OF PRODUCING OPTICALLY ACTIVE AMINO ACID | DAO, RCC2, AADAT | TACR3 1446/4885ENPEP 243/4885CTSK 667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.