Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.47 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.35 |
| ▸ | GAPDH | P04406 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LSS | P48449 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | SQLE | Q14534 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3376001 | 0.88 | LSS (0.40) | KDM1AMAPTLSSSPHK1SQLE | |
| SCHEMBL3375999 | 0.88 | LSS (0.40) | KDM1AMAPTLSSSPHK1SQLE | |
| SCHEMBL1658396 | 0.88 | KDM1A (0.41) | PTPN1KDM1ALSSSQLE | |
| SCHEMBL1658397 | 0.88 | KDM1A (0.41) | PTPN1KDM1ALSSSQLE | |
| SCHEMBL18879142 | 0.85 | OPRM1 (0.47) | PTPN1KDM1AACE2LSSALDH1A1 | |
| SCHEMBL8978484 | 0.85 | PTPN1 (0.67) | PTPN1KDM1AALOX15PTGS1PDE4A | |
| SCHEMBL8978488 | 0.85 | PTPN1 (0.67) | PTPN1KDM1AALOX15PTGS1PDE4A | |
| SCHEMBL8978516 | 0.85 | ALOX15 (0.52) | PTPN1KDM1AMAPTALDH1A1ALOX15 | |
| SCHEMBL8978519 | 0.85 | ALOX15 (0.52) | PTPN1KDM1AMAPTALDH1A1ALOX15 | |
| SCHEMBL18879102 | 0.83 | PTPN1 (0.44) | PTPN1KDM1AACE2TRPA1DDAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2682746-B1 | Methods for the diagnosis of ovarian cancer health states and risk of ovarian cancer health states | PHENOMENOME DISCOVERIES INC (CA) | 2017-05-24 | — | — | EP | disclosed |