SCHEMBL1888009

SCHEMBL1888009

OPOc1cccc(-c2ccccc2)c1-c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HNF4A P41235 1/20 0.38
ALDH1A1 P00352 3/20 0.38
HSD17B10 Q99714 2/20 0.38
HPGD P15428 1/20 0.38
BCL2L1 Q07817 1/20 0.38
HDAC4 P56524 1/20 0.37
HDAC2 Q92769 1/20 0.37
HDAC8 Q9BY41 1/20 0.37
HDAC6 Q9UBN7 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
TP53 P04637 1/20 0.36
MAPK1 P28482 1/20 0.36
RAB9A P51151 1/20 0.36
NCOA1 Q15788 1/20 0.36
NCOA3 Q9Y6Q9 1/20 0.36
BACE1 P56817 1/20 0.34
DPP4 P27487 1/20 0.34
PDCD1 Q15116 1/20 0.34
CD274 Q9NZQ7 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1888008 0.85 RAB9A (0.38) HNF4AALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL2001065 0.81 PTPN5 (0.35) ALDH1A1TDP1HRH1HTR7RXRA
SCHEMBL9064517 0.81 PSMB5 (0.38) ALDH1A1HSD17B10HPGDTDP1L3MBTL1
SCHEMBL30673426 0.78 NCOA1 (0.46) HNF4AALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL8602820 0.78 NCOA1 (0.46) HNF4AALDH1A1HSD17B10HPGDBCL2L1
SCHEMBL1997519 0.77 ALOX5 (0.39) ALDH1A1DPP4PDCD1CD274KDM4E
SCHEMBL1898406 0.75 IDO1 (0.33) ALDH1A1L3MBTL1RAB9APDCD1CD274
SCHEMBL29604346 0.75 INPPL1 (0.52) HNF4AALDH1A1HSD17B10HPGDHDAC4
SCHEMBL4451434 0.75 INPPL1 (0.52) HNF4AALDH1A1HSD17B10HPGDHDAC4
SCHEMBL1880866 0.75 RARB (0.40) ALDH1A1HSD17B10TP53LMNAADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7947342-B2 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2011-05-24 US disclosed
US-20090027586-A1 Thermoplastic Resin Composition, and Liquid Crystal Display Component Thereof or Information Recording Media Component Thereof POLYPLASTICS CO., LTD. (JP) 2009-01-29 US disclosed
EP-2012150-A1 POLARIZING PLATE PROTECTION FILM, METHOD FOR PRODUCING THE SAME, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY Konica Minolta Opto, Inc. (JP) 2009-01-07 EP disclosed
EP-1992666-A1 THERMOPLASTIC RESIN COMPOSITION AND LIQUID CRYSTAL DISPLAY PART OR INFORMATION RECORDING MEDIUM PART USING THE COMPOSITION Polyplastics Co., Ltd. (JP) 2008-11-19 EP disclosed
US-20070254115-A1 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2007-11-01 US disclosed
EP-0510689-A1 Hydrocyanation of pentenenitriles using cyanohydrins E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-10-28 EP disclosed
US-5107012-A Using an additive to promote dissociation of the cyanohydrin, a nickel complex catalyst and catalyst promoter; slurrying E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-04-21 US disclosed