Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 17/20 | 0.48 |
| ▸ | BCHE | P06276 | 16/20 | 0.48 |
| ▸ | ACHE | P22303 | 16/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18880312 | 0.88 | BCHE (0.53) | BACE1BCHEACHE | |
| SCHEMBL16305523 | 0.86 | SIGMAR1 (0.52) | BACE1BCHEACHE | |
| SCHEMBL15995566 | 0.86 | SIGMAR1 (0.52) | BACE1BCHEACHE | |
| SCHEMBL16293637 | 0.81 | BCHE (0.59) | BACE1BCHEACHE | |
| SCHEMBL16305485 | 0.74 | DRD2 (0.55) | BACE1 | |
| SCHEMBL16293072 | 0.71 | TMEM97 (0.45) | BACE1ACHE | |
| SCHEMBL16293073 | 0.71 | TMEM97 (0.45) | BACE1ACHE | |
| SCHEMBL16006932 | 0.71 | TMEM97 (0.45) | BACE1ACHE | |
| SCHEMBL16297309 | 0.70 | KMT2A (0.48) | — | |
| SCHEMBL16303321 | 0.70 | KMT2A (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3170811-A1 | ETHYL PYRIDINE-4-CARBOXYLATE COMPOUND AS INHIBITOR OF HISTONE DEMETHYLASES | Gilead Sciences, Inc. (US) | 2017-05-24 | — | — | EP | disclosed |