Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 9/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16303336 | 1.00 | CACNA1B (0.38) | CACNA1BKDM4EALDH1A1NPSR1LNPEP | |
| SCHEMBL16293754 | 1.00 | CACNA1B (0.38) | CACNA1BKDM4EALDH1A1NPSR1LNPEP | |
| SCHEMBL16292657 | 0.76 | SIRT2 (0.34) | ALDH1A1 | |
| SCHEMBL16292659 | 0.76 | SIRT2 (0.34) | ALDH1A1 | |
| SCHEMBL18880294 | 0.69 | KDM5B (0.33) | KDM4EALDH1A1 | |
| SCHEMBL16292658 | 0.68 | KDM5B (0.40) | KDM4EALDH1A1MAPK1 | |
| SCHEMBL16293837 | 0.67 | KDM5B (0.37) | ALDH1A1 | |
| SCHEMBL16293836 | 0.67 | KDM5B (0.37) | ALDH1A1 | |
| SCHEMBL18880295 | 0.66 | KDM5B (0.51) | CACNA1BALDH1A1 | |
| SCHEMBL1953590 | 0.65 | MMP2 (0.36) | CACNA1BKDM4EALDH1A1NPSR1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2961736-B1 | INHIBITORS OF HISTONE DEMETHYLASES | GILEAD SCIENCES INC (US) | 2018-04-11 | — | — | EP | disclosed |
| EP-3170811-A1 | ETHYL PYRIDINE-4-CARBOXYLATE COMPOUND AS INHIBITOR OF HISTONE DEMETHYLASES | Gilead Sciences, Inc. (US) | 2017-05-24 | — | — | EP | disclosed |