Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | Q9HBH1 | 1/20 | 0.32 | |
| ▸ | FAAH | O00519 | 5/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18771504 | 0.99 | ALDH1A1 (0.37) | ALDH1A1LMNAUSP2CYP3A4MAPT | |
| SCHEMBL15721660 | 0.84 | CTSK (0.39) | ALDH1A1LMNAUSP2CYP3A4MAPT | |
| SCHEMBL2045176 | 0.78 | ALDH1A1 (0.51) | ALDH1A1LMNAUSP2CYP3A4MAPT | |
| SCHEMBL2047122 | 0.78 | ALDH1A1 (0.51) | ALDH1A1LMNAUSP2CYP3A4MAPT | |
| SCHEMBL25698859 | 0.77 | ALDH1A1 (0.45) | ALDH1A1LMNAUSP2CYP3A4MAPT | |
| SCHEMBL27734590 | 0.76 | ALDH1A1 (0.49) | ALDH1A1LMNAUSP2CYP3A4MAPT | |
| SCHEMBL731077 | 0.76 | ALDH1A1 (0.49) | ALDH1A1LMNAUSP2CYP3A4MAPT | |
| SCHEMBL7867821 | 0.73 | ALDH1A1 (0.51) | ALDH1A1LMNAUSP2CYP3A4MAPT | |
| SCHEMBL4016538 | 0.73 | ALDH1A1 (0.55) | ALDH1A1LMNAUSP2CYP3A4MAPT | |
| SCHEMBL2431239 | 0.73 | ALDH1A1 (0.44) | ALDH1A1LMNAUSP2CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9655944-B2 | Inhibitors of hepatitis C virus | GILEAD SCIENCES, INC. (US) | 2017-05-23 | — | — | US | disclosed |