Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.31 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.31 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.31 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.31 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.31 |
| ▸ | BRS3 | P32247 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15423481 | 0.74 | ATM (0.34) | SMN1; SMN2PIK3CDATMCHRNB2CHRNA3 | |
| SCHEMBL16350278 | 0.72 | ATM (0.33) | SMN1; SMN2PIK3CDATM | |
| SCHEMBL18931231 | 0.67 | — | — | |
| SCHEMBL14339364 | 0.67 | OGA (0.33) | ATM | |
| SCHEMBL15423477 | 0.66 | CHRNB2 (0.48) | SMN1; SMN2PIK3CDCHRNB2CHRNA3CHRNA4 | |
| SCHEMBL16316176 | 0.66 | SMN1; SMN2 (0.30) | SMN1; SMN2 | |
| SCHEMBL16350197 | 0.66 | SMN1; SMN2 (0.30) | SMN1; SMN2 | |
| SCHEMBL220386 | 0.64 | — | — | |
| SCHEMBL14145678 | 0.64 | — | — | |
| SCHEMBL21129419 | 0.63 | HCRTR2 (0.34) | PIK3CDHCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9655944-B2 | Inhibitors of hepatitis C virus | GILEAD SCIENCES, INC. (US) | 2017-05-23 | — | — | US | disclosed |