Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RECQL | P46063 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.56 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23191108 | 0.97 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL17933702 | 0.96 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL17933710 | 0.93 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL16552182 | 0.93 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL17933708 | 0.91 | HDAC3 (0.60) | ALDH1A1SMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL23191099 | 0.90 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL17933707 | 0.90 | HDAC3 (0.59) | ALDH1A1SMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL23191043 | 0.89 | ALDH1A1 (0.65) | ALDH1A1SMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL17933616 | 0.89 | HDAC3 (0.58) | ALDH1A1SMN1; SMN2KDM4ENPC1POLB | |
| SCHEMBL14091141 | 0.89 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2KDM4ENPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170143703-A1 | TOXIC RNA INHIBITORS SELF-ASSEMBLED IN SITU | THE SCRIPPS RESEARCH INSTITUTE | 2017-05-25 | — | — | US | disclosed |