Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 2/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.34 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.34 |
| ▸ | EDNRA | P25101 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.33 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.33 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.33 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25834108 | 1.00 | FFAR4 (0.35) | FFAR4KLK7PTGER4PTGER3PTGER2 | |
| SCHEMBL17318675 | 0.89 | FFAR4 (0.38) | FFAR4PTGER4PTGER3PTGER2EDNRA | |
| SCHEMBL19493270 | 0.87 | TP53 (0.32) | BCHECNR2 | |
| SCHEMBL29424475 | 0.84 | KLK7 (0.35) | FFAR4KLK7L3MBTL1FFAR1MAOB | |
| SCHEMBL29424477 | 0.84 | KLK7 (0.35) | FFAR4KLK7L3MBTL1FFAR1MAOB | |
| SCHEMBL1902732 | 0.84 | KLK7 (0.35) | FFAR4KLK7L3MBTL1FFAR1MAOB | |
| SCHEMBL20434247 | 0.79 | L3MBTL1 (0.33) | FFAR4KLK7PTGER4PTGER3PTGER2 | |
| SCHEMBL18406736 | 0.78 | L3MBTL1 (0.33) | FFAR4KLK7PTGER4PTGER3PTGER2 | |
| SCHEMBL18406660 | 0.78 | L3MBTL1 (0.33) | FFAR4KLK7PTGER4PTGER3PTGER2 | |
| SCHEMBL18406744 | 0.77 | TLR9 (0.32) | FFAR4KLK7PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9890159-B2 | Process for making duocarmycin prodrugs | SYNTHON BIOPHARMACEUTICALS B.V. (NL) | 2018-02-13 | — | — | US | disclosed |
| US-20170145006-A1 | PROCESS FOR MAKING DUOCARMYCIN PRODRUGS | SYNTHON BIOPHARMACEUTICALS B.V. (NL) | 2017-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170145006-A1 | PROCESS FOR MAKING DUOCARMYCIN PRODRUGS | UMPS, UNG, DNASE1 | FFAR4 2695/4885KLK7 1302/4885PTGER4 4723/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.