SCHEMBL18884279

SCHEMBL18884279

CCCN(C(=O)CSC)c1cn(-c2cccnc2)nc1Cl

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
DGAT1 O75907 1/20 0.35
TP53 P04637 1/20 0.33
MAPK1 P28482 1/20 0.32
POLB P06746 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
ELANE P08246 1/20 0.32
ADORA3 P0DMS8 2/20 0.32
USP2 O75604 1/20 0.31
ATM Q13315 1/20 0.31
MAT2A P31153 1/20 0.31
F2 P00734 1/20 0.31
CYP1A2 P05177 1/20 0.31
HPGD P15428 1/20 0.31
CYP2C19 P33261 1/20 0.31
KMT2A Q03164 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14904663 0.92 ALDH1A1 (0.40) ALDH1A1NPC1RAB9ADGAT1TP53
SCHEMBL15356918 0.90 NPC1 (0.36) ALDH1A1NPC1RAB9ADGAT1TP53
SCHEMBL4967544 0.89 L3MBTL1 (0.36) ALDH1A1NPC1RAB9ADGAT1MAPK1
SCHEMBL14901007 0.86 ALDH1A1 (0.36) ALDH1A1NPC1RAB9ADGAT1MAPK1
SCHEMBL14904605 0.85 TP53 (0.34) ALDH1A1NPC1RAB9ADGAT1TP53
SCHEMBL15356758 0.85 ALDH1A1 (0.35) ALDH1A1NPC1RAB9ADGAT1MAPK1
SCHEMBL2691588 0.85 ALDH1A1 (0.39) ALDH1A1NPC1RAB9ADGAT1MAPK1
SCHEMBL15356823 0.85 TP53 (0.34) ALDH1A1NPC1RAB9ADGAT1TP53
SCHEMBL15910421 0.84 TP53 (0.36) ALDH1A1NPC1RAB9ADGAT1TP53
SCHEMBL18884333 0.84 TP53 (0.34) ALDH1A1NPC1RAB9ADGAT1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9655365-B2 Pesticidal compositions and processes related thereto DOW AGROSCIENCES LLC (US) 2017-05-23 US disclosed