Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | PRKACG | P22612 | 1/20 | 0.32 |
| ▸ | PRKACB | P22694 | 1/20 | 0.32 |
| ▸ | TSPO | P30536 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23438417 | 0.80 | KDM4E (0.34) | KDM4EATML3MBTL1HDAC4AKR1C4 | |
| SCHEMBL16901212 | 0.78 | L3MBTL1 (0.61) | KDM4EATML3MBTL1HDAC4AKR1C4 | |
| SCHEMBL364704 | 0.78 | L3MBTL1 (0.61) | KDM4EATML3MBTL1HDAC4AKR1C4 | |
| SCHEMBL21709235 | 0.78 | L3MBTL1 (0.61) | KDM4EATML3MBTL1HDAC4AKR1C4 | |
| SCHEMBL19723392 | 0.78 | L3MBTL1 (0.61) | KDM4EATML3MBTL1HDAC4AKR1C4 | |
| SCHEMBL21152046 | 0.78 | L3MBTL1 (0.61) | KDM4EATML3MBTL1HDAC4AKR1C4 | |
| SCHEMBL23282789 | 0.78 | TSPO (0.39) | KDM4EATML3MBTL1HDAC4AKR1C4 | |
| SCHEMBL21116842 | 0.78 | KDM4E (0.37) | KDM4EATML3MBTL1HDAC4AKR1C4 | |
| SCHEMBL21578499 | 0.77 | L3MBTL1 (0.64) | KDM4EATML3MBTL1HDAC4RXRA | |
| SCHEMBL15850636 | 0.77 | L3MBTL1 (0.64) | KDM4EATML3MBTL1HDAC4RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2517274-B1 | COMPOSITIONS COMPRISING POLYMERIC BINDERS | MERCK PATENT GMBH (DE) | 2017-05-24 | — | — | EP | disclosed |