Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 19/20 | 0.62 |
| ▸ | REN | P00797 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14164206 | 0.86 | CTSD (0.57) | CTSDREN | |
| SCHEMBL17758184 | 0.81 | CTSD (0.92) | CTSD | |
| SCHEMBL17758181 | 0.81 | CTSD (0.92) | CTSD | |
| SCHEMBL18745905 | 0.81 | CTSD (0.87) | CTSDREN | |
| SCHEMBL15606240 | 0.81 | CTSD (0.87) | CTSDREN | |
| SCHEMBL16990489 | 0.81 | CTSD (0.87) | CTSDREN | |
| SCHEMBL16990486 | 0.81 | CTSD (0.87) | CTSDREN | |
| SCHEMBL20495546 | 0.81 | CTSD (0.87) | CTSDREN | |
| SCHEMBL16990484 | 0.81 | CTSD (0.87) | CTSDREN | |
| SCHEMBL16990574 | 0.81 | CTSD (0.87) | CTSDREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170145060-A9 | MEANS AND METHODS FOR BREAKING NONCOVALENT BINDING INTERACTIONS BETWEEN MOLECULES | HET NEDERLANDS KANKER INSTITUUT (NL) | 2017-05-25 | — | — | US | disclosed |