Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16990489 | 1.00 | CTSD (0.87) | CTSDREN | |
| SCHEMBL20495546 | 1.00 | CTSD (0.87) | CTSDREN | |
| SCHEMBL16990486 | 1.00 | CTSD (0.87) | CTSDREN | |
| SCHEMBL16990574 | 1.00 | CTSD (0.87) | CTSDREN | |
| SCHEMBL15606240 | 1.00 | CTSD (0.87) | CTSDREN | |
| SCHEMBL18745905 | 1.00 | CTSD (0.87) | CTSDREN | |
| SCHEMBL16990507 | 0.95 | CTSD (0.79) | CTSDREN | |
| SCHEMBL16990512 | 0.95 | CTSD (0.79) | CTSDREN | |
| SCHEMBL16997411 | 0.95 | CTSD (0.79) | CTSDREN | |
| SCHEMBL18661814 | 0.95 | CTSD (0.79) | CTSDREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10077288-B2 | Hydroxystatin derivatives for the treatment of arthrosis | MERCK PATENT GMBH (DE) | 2018-09-18 | — | — | US | claimed |
| EP-2877485-B1 | HYDROXYSTATIN DERIVATIVES FOR TREATMENT OF ARTHROSIS | MERCK PATENT GMBH (DE) | 2018-03-14 | — | — | EP | claimed |
| US-9624264-B2 | Hydroxystatin derivatives for the treatment of arthrosis | MERCK PATENT GMBH (DE) | 2017-04-18 | — | — | US | claimed |
| US-20170081361-A1 | HYDROXYSTATIN DERIVATIVES FOR THE TREATMENT OF ARTHROSIS | MERCK PATENT GMBH (DE) | 2017-03-23 | — | — | US | claimed |
| US-20150225451-A1 | HYDROXYSTATIN DERIVATIVES FOR THE TREATMENT OF ARTHROSIS | MERCK PATENT GMBH (DE) | 2015-08-13 | — | — | US | claimed |
| US-10077288-B2 | Hydroxystatin derivatives for the treatment of arthrosis | MERCK PATENT GMBH (DE) | 2018-09-18 | — | — | US | disclosed |
| US-9624264-B2 | Hydroxystatin derivatives for the treatment of arthrosis | MERCK PATENT GMBH (DE) | 2017-04-18 | — | — | US | disclosed |
| US-20170081361-A1 | HYDROXYSTATIN DERIVATIVES FOR THE TREATMENT OF ARTHROSIS | MERCK PATENT GMBH (DE) | 2017-03-23 | — | — | US | disclosed |
| US-20150225451-A1 | HYDROXYSTATIN DERIVATIVES FOR THE TREATMENT OF ARTHROSIS | MERCK PATENT GMBH (DE) | 2015-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170081361-A1 | HYDROXYSTATIN DERIVATIVES FOR THE TREATMENT OF ARTHROSIS | CTSD, CTSB, CTSZ | CTSD 1/4885REN 779/4885 |
| US-10077288-B2 | Hydroxystatin derivatives for the treatment of arthrosis | CTSD, CTSB, CTSZ | CTSD 1/4885REN 779/4885 |
| US-20150225451-A1 | HYDROXYSTATIN DERIVATIVES FOR THE TREATMENT OF ARTHROSIS | CTSD, CTSB, CTSZ | CTSD 1/4885REN 779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.