Tert-Butylbenzene

Tert-Butylbenzene

SCHEMBL337648

CC(C)(C)c1ccccc1.c1ccccc1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.55
TSHR P16473 3/20 0.53
ALDH1A1 P00352 3/20 0.50
TAAR1 Q96RJ0 1/20 0.50
LMNA P02545 1/20 0.50
TYR P14679 1/20 0.50
ALOX15 P16050 1/20 0.50
ESR1 P03372 2/20 0.48
ESR2 Q92731 2/20 0.48
CYP3A4 P08684 1/20 0.48
KCNN4 O15554 3/20 0.48
MAPT P10636 2/20 0.46
KMT2A Q03164 1/20 0.46
TDP1 Q9NUW8 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
BCHE P06276 1/20 0.44
ACHE P22303 1/20 0.44
CYP2C19 P33261 1/20 0.44
HIF1A Q16665 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tert-Butylbenzene SCHEMBL2568053 1.00 MAPK1 (0.55) MAPK1TSHRALDH1A1TAAR1LMNA
Tert-Butylbenzene SCHEMBL22264597 1.00 MAPK1 (0.55) MAPK1TSHRALDH1A1TAAR1LMNA
Tert-Butylbenzene SCHEMBL18889 1.00 MAPK1 (0.55) MAPK1TSHRALDH1A1TAAR1LMNA
Tert-Butylbenzene SCHEMBL22264599 1.00 MAPK1 (0.55) MAPK1TSHRALDH1A1TAAR1LMNA
Tert-Butylbenzene SCHEMBL16583175 0.97 MAPK1 (0.52) MAPK1TSHRALDH1A1TAAR1LMNA
Tert-Butylbenzene SCHEMBL309340 0.97 LMNA (0.55) MAPK1TSHRALDH1A1TAAR1LMNA
Tert-Butylbenzene SCHEMBL11852689 0.97 MAPK1 (0.52) MAPK1TSHRALDH1A1TAAR1LMNA
Tert-Butylbenzene SCHEMBL975494 0.97 MAPK1 (0.52) MAPK1TSHRALDH1A1TAAR1LMNA
Tert-Butylbenzene SCHEMBL6537004 0.97 MAPK1 (0.52) MAPK1TSHRALDH1A1TAAR1LMNA
Tert-Butylbenzene SCHEMBL5921915 0.97 MAPK1 (0.52) MAPK1TSHRALDH1A1TAAR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116918123-A Nonaqueous electrolyte, nonaqueous electrolyte battery, and compound 中央硝子株式会社 2023-10-20 CN claimed
US-8097764-B2 Methods of isomerizing xylenes with a catalyst reduced in the presence of hydrogen and a base CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2012-01-17 US claimed
US-20110046428-A1 Methods of Isomerizing Xylenes with a Catalyst Reduced in the Presence of Hydrogen and a Base CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2011-02-24 US claimed
CN-116918123-A Nonaqueous electrolyte, nonaqueous electrolyte battery, and compound 中央硝子株式会社 2023-10-20 CN disclosed
CN-115504999-A Polycyclic compound and organic electroluminescent device thereof 中国科学技术大学 2022-12-23 CN disclosed
US-8097764-B2 Methods of isomerizing xylenes with a catalyst reduced in the presence of hydrogen and a base CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2012-01-17 US disclosed
US-20110046428-A1 Methods of Isomerizing Xylenes with a Catalyst Reduced in the Presence of Hydrogen and a Base CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2011-02-24 US disclosed
US-7851664-B2 Methods of isomerizing xylenes with a catalyst reduced in the presence of hydrogen and a base CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) 2010-12-14 US disclosed
US-20090163752-A1 Methods of isomerizing xylenes with a catalyst reduced in the presence of hydrogen and a base CHEVRON PHILLIPS CHEMICAL COMPANY LP 2009-06-25 US disclosed
CN-101265213-A Method for preparing alkylcyanophenyl SOUTH CENTRAL UNIVERSITY FOR N (CN) 2008-09-17 CN disclosed