Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 11/20 | 0.73 |
| ▸ | DAPK3 | O43293 | 5/20 | 0.63 |
| ▸ | PIM1 | P11309 | 5/20 | 0.63 |
| ▸ | GSK3A | P49840 | 5/20 | 0.63 |
| ▸ | GSK3B | P49841 | 5/20 | 0.63 |
| ▸ | PLK4 | O00444 | 4/20 | 0.63 |
| ▸ | CHEK2 | O96017 | 4/20 | 0.63 |
| ▸ | CDK1 | P06493 | 4/20 | 0.63 |
| ▸ | CDK2 | P24941 | 4/20 | 0.63 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.63 |
| ▸ | CSNK1D | P48730 | 4/20 | 0.63 |
| ▸ | CSNK2A1 | P68400 | 4/20 | 0.63 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.63 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.63 |
| ▸ | PLK3 | Q9H4B4 | 4/20 | 0.63 |
| ▸ | PRKACA | P17612 | 4/20 | 0.63 |
| ▸ | KDR | P35968 | 4/20 | 0.63 |
| ▸ | RPS6KA3 | P51812 | 4/20 | 0.63 |
| ▸ | PLK1 | P53350 | 3/20 | 0.63 |
| ▸ | SGK2 | Q9HBY8 | 3/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18889266 | 0.84 | RIPK1 (1.00) | RIPK1NPC1RAB9AL3MBTL1KDM4E | |
| SCHEMBL18889276 | 0.81 | RIPK1 (1.00) | RIPK1NPC1RAB9AL3MBTL1KDM4E | |
| SCHEMBL18889272 | 0.80 | RIPK1 (0.64) | RIPK1MAPK1NPC1RAB9AKDM4E | |
| SCHEMBL18931468 | 0.80 | RIPK1 (0.64) | RIPK1MAPK1NPC1RAB9AKDM4E | |
| SCHEMBL7934399 | 0.79 | GSK3A (0.78) | DAPK3PIM1GSK3AGSK3BPLK4 | |
| SCHEMBL18889280 | 0.78 | RIPK1 (1.00) | RIPK1MAPK1NPC1RAB9AKDM4E | |
| SCHEMBL18904577 | 0.78 | RIPK1 (0.88) | RIPK1NPC1RAB9AL3MBTL1 | |
| SCHEMBL18889250 | 0.78 | SELE (0.53) | RIPK1NPC1RAB9AICAM1SELE | |
| SCHEMBL7050653 | 0.78 | GSK3A (1.00) | DAPK3PIM1GSK3AGSK3BPLK4 | |
| SCHEMBL18904581 | 0.77 | RIPK1 (0.77) | RIPK1MAPK1NPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3176163-B1 | NOVEL INDENE DERIVATIVE, PREPARATION METHOD FOR SAME, AND PHARMACEUTICAL COMPOSITION, FOR PREVENTING OR TREATING RETINAL DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT | IAC IN NAT UNIV CHUNGNAM (KR) | 2019-04-17 | — | — | EP | claimed |
| EP-3176163-A1 | NOVEL INDENE DERIVATIVE, PREPARATION METHOD FOR SAME, AND PHARMACEUTICAL COMPOSITION, FOR PREVENTING OR TREATING RETINAL DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT | The Industry & Academic Cooperation in Chungnam National University (IAC) (KR) | 2017-06-07 | — | — | EP | claimed |
| US-20170152268-A1 | NOVEL INDENE DERIVATIVE, PREPARATION METHOD FOR SAME, AND PHARMACEUTICAL COMPOSITION, FOR PREVENTING OR TREATING RETINAL DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT | MOTHER'S PHARMACEUTICAL CO., LTD. (KR) | 2017-06-01 | — | — | US | claimed |
| EP-3176163-B1 | NOVEL INDENE DERIVATIVE, PREPARATION METHOD FOR SAME, AND PHARMACEUTICAL COMPOSITION, FOR PREVENTING OR TREATING RETINAL DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT | IAC IN NAT UNIV CHUNGNAM (KR) | 2019-04-17 | — | — | EP | disclosed |
| EP-3176163-B1 | NOVEL INDENE DERIVATIVE, PREPARATION METHOD FOR SAME, AND PHARMACEUTICAL COMPOSITION, FOR PREVENTING OR TREATING RETINAL DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT | IAC IN NAT UNIV CHUNGNAM (KR) | 2019-04-17 | — | — | EP | disclosed |
| EP-3176163-A1 | NOVEL INDENE DERIVATIVE, PREPARATION METHOD FOR SAME, AND PHARMACEUTICAL COMPOSITION, FOR PREVENTING OR TREATING RETINAL DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT | The Industry & Academic Cooperation in Chungnam National University (IAC) (KR) | 2017-06-07 | — | — | EP | disclosed |
| EP-3176163-A1 | NOVEL INDENE DERIVATIVE, PREPARATION METHOD FOR SAME, AND PHARMACEUTICAL COMPOSITION, FOR PREVENTING OR TREATING RETINAL DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT | The Industry & Academic Cooperation in Chungnam National University (IAC) (KR) | 2017-06-07 | — | — | EP | disclosed |
| US-20170152268-A1 | NOVEL INDENE DERIVATIVE, PREPARATION METHOD FOR SAME, AND PHARMACEUTICAL COMPOSITION, FOR PREVENTING OR TREATING RETINAL DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT | MOTHER'S PHARMACEUTICAL CO., LTD. (KR) | 2017-06-01 | — | — | US | disclosed |
| US-20170152268-A1 | NOVEL INDENE DERIVATIVE, PREPARATION METHOD FOR SAME, AND PHARMACEUTICAL COMPOSITION, FOR PREVENTING OR TREATING RETINAL DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT | MOTHER'S PHARMACEUTICAL CO., LTD. (KR) | 2017-06-01 | — | — | US | disclosed |
| US-20170152268-A1 | NOVEL INDENE DERIVATIVE, PREPARATION METHOD FOR SAME, AND PHARMACEUTICAL COMPOSITION, FOR PREVENTING OR TREATING RETINAL DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT | MOTHER'S PHARMACEUTICAL CO., LTD. (KR) | 2017-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170152268-A1 | NOVEL INDENE DERIVATIVE, PREPARATION METHOD FOR SAME, AND PHARMACEUTICAL COMPOSITION, FOR PREVENTING OR TREATING RETINAL DISEASES, CONTAINING SAME AS ACTIVE INGREDIENT | RIPK1, RIPK2, RIPK3 | RIPK1 1/4885DAPK3 35/4885PIM1 406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.